STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFF21348.1Type VII secretion-associated serine protease mycosin. (434 aa)    
Predicted Functional Partners:
SFF58662.1
Subtilase family protein.
  
  
  0.805
SFE39477.1
Subtilase family protein; Belongs to the peptidase S8 family.
  
     0.773
SFF21324.1
Conserved DNA-binding protein YbaB; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.
       0.773
SFF21336.1
Hypothetical protein.
       0.773
SFE91268.1
Subtilase family protein.
  
     0.771
SFF21364.1
Hypothetical protein.
   
  0.748
SFF21376.1
Hypothetical protein.
       0.681
SFF21389.1
WXG100 family type VII secretion target; Belongs to the WXG100 family.
     
 0.636
SFF21404.1
WXG100 family type VII secretion target; Belongs to the WXG100 family.
     
 0.620
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
   0.576
Your Current Organism:
Actinoplanes philippinensis
NCBI taxonomy Id: 35752
Other names: A. philippinensis, ATCC 12427, DSM 43019, IFO 13878, JCM 3001, NBRC 13878, NRRL 2506, VKM Ac-842
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