STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliWFlagellar assembly factor FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (132 aa)    
Predicted Functional Partners:
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
 
 
 0.999
SFF53485.1
Flagellar hook-associated protein 3 FlgL; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.996
SFF53462.1
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.984
SFF53477.1
Flagellar hook-associated protein 1 FlgK; Belongs to the flagella basal body rod proteins family.
 
  
 0.975
SFF53257.1
Flagellar motor switch protein FliM.
 
  
 0.948
SFF53446.1
Flagellar protein FliS.
 
  
 0.947
SFF44603.1
Hypothetical protein.
  
 
 0.944
SFF53452.1
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.929
SFF53420.1
Flagellar basal-body rod protein FlgC.
 
 
 0.919
SFF53469.1
FlgN protein.
 
     0.915
Your Current Organism:
Actinoplanes philippinensis
NCBI taxonomy Id: 35752
Other names: A. philippinensis, ATCC 12427, DSM 43019, IFO 13878, JCM 3001, NBRC 13878, NRRL 2506, VKM Ac-842
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