STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFF60091.1Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II. (405 aa)    
Predicted Functional Partners:
SFE41182.1
Amino acid adenylation domain-containing protein.
  
0.991
SFF60076.1
Acyl carrier protein.
 
  0.984
SFF60104.1
Acyl-CoA reductase (LuxC).
 
  0.966
SFE32238.1
Helix-hairpin-helix domain-containing protein.
  
 0.955
SFF60097.1
Acyl-protein synthetase, LuxE.
 
  
 0.950
SFF60083.1
3-oxoacyl-[acyl-carrier protein] reductase.
 
 
  0.856
rplF
Large subunit ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.833
SFE93340.1
Thioester reductase domain-containing protein.
  
 0.798
SFF60111.1
Dolichol-phosphate mannosyltransferase.
   
   0.794
SFE93374.1
Acyl transferase domain-containing protein.
  
 0.789
Your Current Organism:
Actinoplanes philippinensis
NCBI taxonomy Id: 35752
Other names: A. philippinensis, ATCC 12427, DSM 43019, IFO 13878, JCM 3001, NBRC 13878, NRRL 2506, VKM Ac-842
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.