STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFF62489.1uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. (402 aa)    
Predicted Functional Partners:
SFF53767.1
Uroporphyrinogen III methyltransferase / synthase.
 
 
0.999
SFF05696.1
Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase.
 
 
0.998
SFF22595.1
Sirohydrochlorin ferrochelatase.
 
 0.997
SFF44806.1
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.997
SFF42702.1
Sulfate adenylyltransferase.
 
  
 0.996
SFF48574.1
Sirohydrochlorin ferrochelatase.
 
 
 0.995
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.995
SFF53776.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.989
SFF22606.1
uroporphyrinogen-III synthase.
 
 
 0.985
SFF48598.1
Sulfite reductase (ferredoxin); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.985
Your Current Organism:
Actinoplanes philippinensis
NCBI taxonomy Id: 35752
Other names: A. philippinensis, ATCC 12427, DSM 43019, IFO 13878, JCM 3001, NBRC 13878, NRRL 2506, VKM Ac-842
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