STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFF67283.1Stage II sporulation protein E (SpoIIE). (390 aa)    
Predicted Functional Partners:
SFF12920.1
Serine phosphatase RsbU, regulator of sigma subunit.
 
 0.920
SFE32795.1
Signal transduction histidine kinase.
 
 
 0.895
SFF58324.1
Serine phosphatase RsbU, regulator of sigma subunit.
 
 0.894
SFE31455.1
His Kinase A (phospho-acceptor) domain-containing protein.
 
 
 0.868
SFF55611.1
sigma-B regulation protein RsbU (phosphoserine phosphatase).
  
 
 0.851
SFF56810.1
Hypothetical protein/two-component system, OmpR family, KDP operon response regulator KdpE.
  
 
 0.849
SFF59228.1
Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
  0.828
SFF69848.1
PAS domain S-box-containing protein.
  
 0.817
SFF24060.1
PAS domain S-box-containing protein.
  
 
 0.816
SFF30829.1
Response regulator receiver domain-containing protein.
  
 
 0.816
Your Current Organism:
Actinoplanes philippinensis
NCBI taxonomy Id: 35752
Other names: A. philippinensis, ATCC 12427, DSM 43019, IFO 13878, JCM 3001, NBRC 13878, NRRL 2506, VKM Ac-842
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.