STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (736 aa)    
Predicted Functional Partners:
AKE40736.1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.958
folE
GTP cyclohydrolase I.
  
  
 0.954
AKE40740.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
    0.915
folP1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
 0.882
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
     
 0.874
AKE41242.1
Membrane protease subunit, stomatin/prohibitin.
   
 0.870
AKE42199.1
SPFH domain-containing protein.
   
 0.870
clpX
Endopeptidase Clp ATP-binding regulatory subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.865
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase.
  
  
 0.854
AKE40734.1
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4).
       0.844
Your Current Organism:
Corynebacterium kutscheri
NCBI taxonomy Id: 35755
Other names: ATCC 15677, Bacillus pesudotuberculosis murium, Bacterium kutscheri, C. kutscheri, CCUG 27535, CIP 103423, Corynebacterium murium, DSM 20755, IFO 15288, JCM 9385, NBRC 15288, NCTC 11138
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