STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
priA_1Unannotated protein. (194 aa)    
Predicted Functional Partners:
hisF
Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
0.999
hisI
Unannotated protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
 
 
 0.998
hisH
Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
 
 0.998
hisB
Unannotated protein.
 
 
 0.987
trpC_2
Unannotated protein; Belongs to the TrpC family.
  
 
 0.978
hisG
Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
 
 
 0.976
hisD
Unannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
 
 0.974
GCA_001044155_01399
Unannotated protein.
 
 
 0.974
trpC_1
Unannotated protein.
  
 
 0.964
impA
Unannotated protein.
  
  
 0.958
Your Current Organism:
Corynebacterium pilosum
NCBI taxonomy Id: 35756
Other names: ATCC 29592, C. pilosum, CCUG 27193, CIP 103422, DSM 20521, IFO 15285, JCM 3714, NBRC 15285, NCTC 11862
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.