Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prpBUnannotated protein; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (307 aa)    
Predicted Functional Partners:
prpD
Unannotated protein.
 
  
 0.996
prpC2
Unannotated protein; Belongs to the citrate synthase family.
 
 0.989
gltA
Unannotated protein; Belongs to the citrate synthase family.
  
 0.888
GCA_001044155_02062
Unannotated protein.
  
 
 0.862
bclA
Unannotated protein.
  
 
 0.862
leuA
Unannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.856
acn
Unannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.855
GCA_001044155_02553
Unannotated protein.
  
 0.855
accC_2
Unannotated protein.
  
 0.854
sdhA
Unannotated protein.
  
 
 0.849
Your Current Organism:
Corynebacterium pilosum
NCBI taxonomy Id: 35756
Other names: ATCC 29592, C. pilosum, CCUG 27193, CIP 103422, DSM 20521, IFO 15285, JCM 3714, NBRC 15285, NCTC 11862
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