STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smgPFAM: protein of unknown function DUF494; KEGG: ilo:IL0020 hypothetical protein; Belongs to the Smg family. (157 aa)    
Predicted Functional Partners:
Ping_0076
TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: pat:Patl_0025 DNA protecting protein DprA.
    
 0.872
Ping_0074
PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: pha:PSHAa0027 DNA topoisomerase.
 
   
 0.861
zapD
Hypothetical protein DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
  
     0.743
tsaC
Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
       0.707
Ping_0077
PFAM: Peptidoglycan-binding LysM; KEGG: sfr:Sfri_0025 peptidoglycan-binding LysM.
 
     0.702
Ping_0858
PFAM: protein of unknown function DUF526; KEGG: ppr:PBPRA0086 hypothetical protein.
  
     0.690
Ping_1127
KEGG: ppr:PBPRA3265 hypothetical membrane protein.
  
     0.678
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.623
Ping_0066
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
     0.616
Ping_0322
PFAM: protein of unknown function DUF1243; KEGG: vpa:VP0096 conserved hypothetical protein.
  
     0.596
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
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