node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ping_0109 | Ping_0110 | Ping_0109 | Ping_0110 | PFAM: electron transport protein SCO1/SenC; KEGG: pat:Patl_4237 electron transport protein SCO1/SenC. | TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: vfi:VF2440 Na(+) driven multidrug efflux pump. | 0.554 |
Ping_0109 | lexA | Ping_0109 | Ping_0108 | PFAM: electron transport protein SCO1/SenC; KEGG: pat:Patl_4237 electron transport protein SCO1/SenC. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.536 |
Ping_0110 | Ping_0109 | Ping_0110 | Ping_0109 | TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: vfi:VF2440 Na(+) driven multidrug efflux pump. | PFAM: electron transport protein SCO1/SenC; KEGG: pat:Patl_4237 electron transport protein SCO1/SenC. | 0.554 |
Ping_0110 | lexA | Ping_0110 | Ping_0108 | TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: vfi:VF2440 Na(+) driven multidrug efflux pump. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.549 |
Ping_0193 | lexA | Ping_0193 | Ping_0108 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.717 |
Ping_0705 | lexA | Ping_0705 | Ping_0108 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: ppr:PBPRA1951 putative haemagglutinin associated protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.778 |
Ping_0914 | Ping_2220 | Ping_0914 | Ping_2220 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | PFAM: YebG family protein; KEGG: sdn:Sden_1719 YebG. | 0.560 |
Ping_0914 | Ping_2235 | Ping_0914 | Ping_2235 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.848 |
Ping_0914 | dinB | Ping_0914 | Ping_1342 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.507 |
Ping_0914 | lexA | Ping_0914 | Ping_0108 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.744 |
Ping_0914 | recA | Ping_0914 | Ping_3381 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.810 |
Ping_2220 | Ping_0914 | Ping_2220 | Ping_0914 | PFAM: YebG family protein; KEGG: sdn:Sden_1719 YebG. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.560 |
Ping_2220 | Ping_2235 | Ping_2220 | Ping_2235 | PFAM: YebG family protein; KEGG: sdn:Sden_1719 YebG. | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.718 |
Ping_2220 | lexA | Ping_2220 | Ping_0108 | PFAM: YebG family protein; KEGG: sdn:Sden_1719 YebG. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.723 |
Ping_2220 | recA | Ping_2220 | Ping_3381 | PFAM: YebG family protein; KEGG: sdn:Sden_1719 YebG. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.510 |
Ping_2235 | Ping_0914 | Ping_2235 | Ping_0914 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.848 |
Ping_2235 | Ping_2220 | Ping_2235 | Ping_2220 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | PFAM: YebG family protein; KEGG: sdn:Sden_1719 YebG. | 0.718 |
Ping_2235 | lexA | Ping_2235 | Ping_0108 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.665 |
Ping_2235 | recA | Ping_2235 | Ping_3381 | Hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.580 |
dinB | Ping_0914 | Ping_1342 | Ping_0914 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.507 |