node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ping_0175 | Ping_0177 | Ping_0175 | Ping_0177 | PFAM: conserved hypothetical protein 245; KEGG: cps:CPS_4093 putative membrane protein. | General secretion pathway ATPase protein; PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: sdn:Sden_2822 peptidoglycan-binding domain 1. | 0.459 |
Ping_0175 | Ping_0178 | Ping_0175 | Ping_0178 | PFAM: conserved hypothetical protein 245; KEGG: cps:CPS_4093 putative membrane protein. | KEGG: ilo:IL1964 general secretion pathway protein B. | 0.459 |
Ping_0175 | cca | Ping_0175 | Ping_0176 | PFAM: conserved hypothetical protein 245; KEGG: cps:CPS_4093 putative membrane protein. | Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.632 |
Ping_0177 | Ping_0175 | Ping_0177 | Ping_0175 | General secretion pathway ATPase protein; PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: sdn:Sden_2822 peptidoglycan-binding domain 1. | PFAM: conserved hypothetical protein 245; KEGG: cps:CPS_4093 putative membrane protein. | 0.459 |
Ping_0177 | Ping_0178 | Ping_0177 | Ping_0178 | General secretion pathway ATPase protein; PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: sdn:Sden_2822 peptidoglycan-binding domain 1. | KEGG: ilo:IL1964 general secretion pathway protein B. | 0.800 |
Ping_0177 | cca | Ping_0177 | Ping_0176 | General secretion pathway ATPase protein; PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: sdn:Sden_2822 peptidoglycan-binding domain 1. | Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.606 |
Ping_0178 | Ping_0175 | Ping_0178 | Ping_0175 | KEGG: ilo:IL1964 general secretion pathway protein B. | PFAM: conserved hypothetical protein 245; KEGG: cps:CPS_4093 putative membrane protein. | 0.459 |
Ping_0178 | Ping_0177 | Ping_0178 | Ping_0177 | KEGG: ilo:IL1964 general secretion pathway protein B. | General secretion pathway ATPase protein; PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: sdn:Sden_2822 peptidoglycan-binding domain 1. | 0.800 |
Ping_0178 | cca | Ping_0178 | Ping_0176 | KEGG: ilo:IL1964 general secretion pathway protein B. | Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.586 |
Ping_0179 | cca | Ping_0179 | Ping_0176 | PFAM: SH3, type 3 domain protein; SMART: SH3 domain protein domain protein; KEGG: eca:ECA3587 putative membrane protein. | Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.736 |
Ping_1189 | Ping_2870 | Ping_1189 | Ping_2870 | KEGG: vfi:VF0751 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta. | PFAM: Stringent starvation protein B; KEGG: vfi:VF2215 stringent starvation protein B. | 0.742 |
Ping_1189 | cca | Ping_1189 | Ping_0176 | KEGG: vfi:VF0751 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta. | Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.702 |
Ping_1189 | metG | Ping_1189 | Ping_1623 | KEGG: vfi:VF0751 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.506 |
Ping_2870 | Ping_1189 | Ping_2870 | Ping_1189 | PFAM: Stringent starvation protein B; KEGG: vfi:VF2215 stringent starvation protein B. | KEGG: vfi:VF0751 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta. | 0.742 |
Ping_2870 | cca | Ping_2870 | Ping_0176 | PFAM: Stringent starvation protein B; KEGG: vfi:VF2215 stringent starvation protein B. | Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.596 |
Ping_2870 | metG | Ping_2870 | Ping_1623 | PFAM: Stringent starvation protein B; KEGG: vfi:VF2215 stringent starvation protein B. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.638 |
birA | cca | Ping_0219 | Ping_0176 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.721 |
birA | dapB | Ping_0219 | Ping_3648 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.654 |
birA | metG | Ping_0219 | Ping_1623 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.548 |
birA | mgsA | Ping_0219 | Ping_0116 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.764 |