Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ping_0179PFAM: SH3, type 3 domain protein; SMART: SH3 domain protein domain protein; KEGG: eca:ECA3587 putative membrane protein. (189 aa)    
Predicted Functional Partners:
cca
Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
 
  
 0.792
Ping_1914
PFAM: protein of unknown function DUF490; KEGG: ppr:PBPRA0380 hypothetical protein.
 
     0.569
hemX
uroporphyrin-III C-methyltransferase HemX; PFAM: protein of unknown function DUF513, hemX; KEGG: yps:YPTB0182 putative uroporphyrin-III C-methyltransferase.
  
     0.531
Ping_3639
PFAM: HemY domain protein; KEGG: ppr:PBPRA3531 hypothetical HemY protein.
  
     0.513
Ping_0954
PFAM: UspA domain protein; KEGG: ppr:PBPRB0088 putative universal stress protein A.
 
    0.509
Ping_1084
PFAM: protein of unknown function DUF177; KEGG: ppr:PBPRA1190 conserved hypothetical protein.
 
     0.473
Ping_0125
PFAM: UspA domain protein; KEGG: ppr:PBPRB0088 putative universal stress protein A.
 
    0.454
Ping_0959
PFAM: UspA domain protein; KEGG: vch:VC0076 universal stress protein A.
 
    0.422
Ping_0066
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
  
 0.417
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
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