STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Ping_0203(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (715 aa)    
Predicted Functional Partners:
Ping_0665
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ppr:PBPRA3081 putative MazG protein.
 
 
 0.934
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.934
Ping_3192
PFAM: Ppx/GppA phosphatase; KEGG: vpa:VP3003 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase.
  
 
 0.925
Ping_0530
(p)ppGpp synthetase I and guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
  
 
0.919
Ping_2413
PFAM: Ppx/GppA phosphatase; KEGG: vpa:VP0572 exopolyphosphatase; Belongs to the GppA/Ppx family.
   
 
 0.914
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.913
Ping_0061
PFAM: adenylate cyclase, class-I; KEGG: ppr:PBPRA3526 putative adenylate cyclase.
     
 0.901
Ping_1109
PFAM: ribonucleotide reductase; KEGG: spt:SPA0586 ribonucleoside-diphosphate reductase 1 beta chain.
   
 
  0.901
Ping_1112
Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 
  0.901
Ping_0740
Ribonucleoside-triphosphate reductase class III catalytic subunit; KEGG: sec:SC4307 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein.
     
  0.900
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
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