| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0061 | Ping_0388 | Ping_0061 | Ping_0388 | PFAM: adenylate cyclase, class-I; KEGG: ppr:PBPRA3526 putative adenylate cyclase. | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | 0.868 |
| Ping_0061 | cpdA | Ping_0061 | Ping_3358 | PFAM: adenylate cyclase, class-I; KEGG: ppr:PBPRA3526 putative adenylate cyclase. | Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.749 |
| Ping_0388 | Ping_0061 | Ping_0388 | Ping_0061 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | PFAM: adenylate cyclase, class-I; KEGG: ppr:PBPRA3526 putative adenylate cyclase. | 0.868 |
| Ping_0388 | Ping_2897 | Ping_0388 | Ping_2897 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | PFAM: Uncharacterised conserved protein UCP006287; KEGG: sdn:Sden_2907 uncharacterised conserved protein UCP006287; Belongs to the UPF0231 family. | 0.759 |
| Ping_0388 | cpdA | Ping_0388 | Ping_3358 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.767 |
| Ping_0388 | rpoA1 | Ping_0388 | Ping_2614 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.868 |
| Ping_0388 | rpoA2 | Ping_0388 | Ping_3499 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.868 |
| Ping_0388 | rpoB | Ping_0388 | Ping_3446 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.892 |
| Ping_0388 | rpoC | Ping_0388 | Ping_3445 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.894 |
| Ping_0388 | rpoD | Ping_0388 | Ping_0310 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.940 |
| Ping_0388 | rpoS | Ping_0388 | Ping_0677 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | RNA polymerase, sigma 38 subunit, RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.731 |
| Ping_0388 | rpoZ | Ping_0388 | Ping_3624 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.880 |
| Ping_2897 | Ping_0388 | Ping_2897 | Ping_0388 | PFAM: Uncharacterised conserved protein UCP006287; KEGG: sdn:Sden_2907 uncharacterised conserved protein UCP006287; Belongs to the UPF0231 family. | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | 0.759 |
| cpdA | Ping_0061 | Ping_3358 | Ping_0061 | Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | PFAM: adenylate cyclase, class-I; KEGG: ppr:PBPRA3526 putative adenylate cyclase. | 0.749 |
| cpdA | Ping_0388 | Ping_3358 | Ping_0388 | Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | 0.767 |
| rpoA1 | Ping_0388 | Ping_2614 | Ping_0388 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | 0.868 |
| rpoA1 | rpoA2 | Ping_2614 | Ping_3499 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.900 |
| rpoA1 | rpoB | Ping_2614 | Ping_3446 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.995 |
| rpoA1 | rpoC | Ping_2614 | Ping_3445 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.991 |
| rpoA1 | rpoD | Ping_2614 | Ping_0310 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.970 |