| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0388 | Ping_0389 | Ping_0388 | Ping_0389 | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | 0.537 |
| Ping_0389 | Ping_0388 | Ping_0389 | Ping_0388 | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: vfi:VF2280 catabolite gene activator Vfr. | 0.537 |
| Ping_0389 | Ping_0618 | Ping_0389 | Ping_0618 | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | KEGG: son:SO2064 hypothetical protein. | 0.410 |
| Ping_0389 | Ping_1108 | Ping_0389 | Ping_1108 | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | PFAM: ferredoxin; KEGG: vvy:VV1242 ferredoxin. | 0.412 |
| Ping_0389 | Ping_2267 | Ping_0389 | Ping_2267 | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | PFAM: 37kDa nucleoid-associated protein; KEGG: vvy:VV1167 nucleoid-associated protein. | 0.403 |
| Ping_0389 | Ping_3305 | Ping_0389 | Ping_3305 | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | 0.442 |
| Ping_0389 | seqA | Ping_0389 | Ping_0878 | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.409 |
| Ping_0389 | thiI | Ping_0389 | Ping_2227 | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.444 |
| Ping_0618 | Ping_0389 | Ping_0618 | Ping_0389 | KEGG: son:SO2064 hypothetical protein. | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | 0.410 |
| Ping_1108 | Ping_0389 | Ping_1108 | Ping_0389 | PFAM: ferredoxin; KEGG: vvy:VV1242 ferredoxin. | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | 0.412 |
| Ping_2267 | Ping_0389 | Ping_2267 | Ping_0389 | PFAM: 37kDa nucleoid-associated protein; KEGG: vvy:VV1167 nucleoid-associated protein. | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | 0.403 |
| Ping_2267 | seqA | Ping_2267 | Ping_0878 | PFAM: 37kDa nucleoid-associated protein; KEGG: vvy:VV1167 nucleoid-associated protein. | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.657 |
| Ping_3305 | Ping_0389 | Ping_3305 | Ping_0389 | Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | 0.442 |
| seqA | Ping_0389 | Ping_0878 | Ping_0389 | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | 0.409 |
| seqA | Ping_2267 | Ping_0878 | Ping_2267 | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | PFAM: 37kDa nucleoid-associated protein; KEGG: vvy:VV1167 nucleoid-associated protein. | 0.657 |
| thiI | Ping_0389 | Ping_2227 | Ping_0389 | [ThiS-adenylate] sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | PFAM: protein of unknown function UPF0270; KEGG: pha:PSHAa2909 hypothetical protein; Belongs to the UPF0270 family. | 0.444 |