node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ping_2104 | Ping_3391 | Ping_2104 | Ping_3391 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.707 |
Ping_2104 | dnaX | Ping_2104 | Ping_2277 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | DNA polymerase III, tau subunit / DNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.428 |
Ping_2104 | polA | Ping_2104 | Ping_3185 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | Fused DNA polymerase 5'->3' exonuclease and 3'->5' polymerase and 3'->5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.644 |
Ping_2104 | rnhA | Ping_2104 | Ping_0496 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.456 |
Ping_2104 | topA | Ping_2104 | Ping_1971 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.633 |
Ping_2104 | xni | Ping_2104 | Ping_2776 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.620 |
Ping_2666 | rnhA | Ping_2666 | Ping_0496 | Oxidoreductase domain protein; PFAM: Semialdehyde dehydrogenase, NAD - binding; oxidoreductase domain protein; KEGG: sru:SRU_0347 oxidoreductase family, NAD-binding Rossmann fold domain protein. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.784 |
Ping_3391 | Ping_2104 | Ping_3391 | Ping_2104 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | 0.707 |
Ping_3391 | dnaX | Ping_3391 | Ping_2277 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase III, tau subunit / DNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.942 |
Ping_3391 | polA | Ping_3391 | Ping_3185 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Fused DNA polymerase 5'->3' exonuclease and 3'->5' polymerase and 3'->5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.621 |
Ping_3391 | rnhA | Ping_3391 | Ping_0496 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.858 |
Ping_3391 | topA | Ping_3391 | Ping_1971 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.938 |
dnaQ | dnaX | Ping_0495 | Ping_2277 | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | DNA polymerase III, tau subunit / DNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.951 |
dnaQ | polA | Ping_0495 | Ping_3185 | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Fused DNA polymerase 5'->3' exonuclease and 3'->5' polymerase and 3'->5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.473 |
dnaQ | rnhA | Ping_0495 | Ping_0496 | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.970 |
dnaX | Ping_2104 | Ping_2277 | Ping_2104 | DNA polymerase III, tau subunit / DNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | 0.428 |
dnaX | Ping_3391 | Ping_2277 | Ping_3391 | DNA polymerase III, tau subunit / DNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.942 |
dnaX | dnaQ | Ping_2277 | Ping_0495 | DNA polymerase III, tau subunit / DNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.951 |
dnaX | polA | Ping_2277 | Ping_3185 | DNA polymerase III, tau subunit / DNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Fused DNA polymerase 5'->3' exonuclease and 3'->5' polymerase and 3'->5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.462 |
dnaX | rnhA | Ping_2277 | Ping_0496 | DNA polymerase III, tau subunit / DNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.532 |