| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0272 | Ping_3434 | Ping_0272 | Ping_3434 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: eba:ebA3193 putative oxidoreductase, FAD-binding. | Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 0.925 |
| Ping_0272 | cysC | Ping_0272 | Ping_0800 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: eba:ebA3193 putative oxidoreductase, FAD-binding. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.801 |
| Ping_0272 | cysD | Ping_0272 | Ping_0796 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: eba:ebA3193 putative oxidoreductase, FAD-binding. | TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: pha:PSHAa0212 ATP-sulfurylase subunit 2. | 0.645 |
| Ping_0272 | cysG | Ping_0272 | Ping_0298 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: eba:ebA3193 putative oxidoreductase, FAD-binding. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.716 |
| Ping_0272 | cysH | Ping_0272 | Ping_3436 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: eba:ebA3193 putative oxidoreductase, FAD-binding. | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.963 |
| Ping_0272 | cysI | Ping_0272 | Ping_3435 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: eba:ebA3193 putative oxidoreductase, FAD-binding. | Sulfite reductase (NADPH) beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.988 |
| Ping_0272 | cysN | Ping_0272 | Ping_0798 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: eba:ebA3193 putative oxidoreductase, FAD-binding. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.816 |
| Ping_2879 | cysC | Ping_2879 | Ping_0800 | PFAM: pyruvate kinase; KEGG: stm:STM1378 pyruvate kinase I (formerly F), fructose stimulated. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.881 |
| Ping_2879 | tuf | Ping_2879 | Ping_3437 | PFAM: pyruvate kinase; KEGG: stm:STM1378 pyruvate kinase I (formerly F), fructose stimulated. | Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.461 |
| Ping_3434 | Ping_0272 | Ping_3434 | Ping_0272 | Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: eba:ebA3193 putative oxidoreductase, FAD-binding. | 0.925 |
| Ping_3434 | cysC | Ping_3434 | Ping_0800 | Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.893 |
| Ping_3434 | cysD | Ping_3434 | Ping_0796 | Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: pha:PSHAa0212 ATP-sulfurylase subunit 2. | 0.909 |
| Ping_3434 | cysG | Ping_3434 | Ping_0298 | Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.754 |
| Ping_3434 | cysH | Ping_3434 | Ping_3436 | Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.999 |
| Ping_3434 | cysI | Ping_3434 | Ping_3435 | Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Sulfite reductase (NADPH) beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.999 |
| Ping_3434 | cysN | Ping_3434 | Ping_0798 | Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.906 |
| Ping_3742 | cysC | Ping_3742 | Ping_0800 | PFAM: flavodoxin/nitric oxide synthase; KEGG: plu:plu0050 protein mioC, involved in modulation of initiation at oriC, initiation of chromosome replication. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.774 |
| Ping_3742 | cysD | Ping_3742 | Ping_0796 | PFAM: flavodoxin/nitric oxide synthase; KEGG: plu:plu0050 protein mioC, involved in modulation of initiation at oriC, initiation of chromosome replication. | TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: pha:PSHAa0212 ATP-sulfurylase subunit 2. | 0.788 |
| Ping_3742 | cysG | Ping_3742 | Ping_0298 | PFAM: flavodoxin/nitric oxide synthase; KEGG: plu:plu0050 protein mioC, involved in modulation of initiation at oriC, initiation of chromosome replication. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.692 |
| Ping_3742 | cysH | Ping_3742 | Ping_3436 | PFAM: flavodoxin/nitric oxide synthase; KEGG: plu:plu0050 protein mioC, involved in modulation of initiation at oriC, initiation of chromosome replication. | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.851 |