| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0080 | Ping_0809 | Ping_0080 | Ping_0809 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | 0.542 |
| Ping_0080 | csrA | Ping_0080 | Ping_3378 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Carbon storage regulator, CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | 0.539 |
| Ping_0080 | hfq | Ping_0080 | Ping_3238 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.516 |
| Ping_0080 | rlmE | Ping_0080 | Ping_0810 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 23S rRNA Um-2552 2'-O-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.848 |
| Ping_0080 | rplK | Ping_0080 | Ping_3450 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.594 |
| Ping_0080 | rsfS | Ping_0080 | Ping_1137 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.488 |
| Ping_0080 | rsmA | Ping_0080 | Ping_1047 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.604 |
| Ping_0809 | Ping_0080 | Ping_0809 | Ping_0080 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.542 |
| Ping_0809 | Ping_0814 | Ping_0809 | Ping_0814 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.485 |
| Ping_0809 | csrA | Ping_0809 | Ping_3378 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | Carbon storage regulator, CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | 0.540 |
| Ping_0809 | hfq | Ping_0809 | Ping_3238 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.540 |
| Ping_0809 | infA | Ping_0809 | Ping_0744 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.522 |
| Ping_0809 | nadD | Ping_0809 | Ping_1188 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.790 |
| Ping_0809 | rlmE | Ping_0809 | Ping_0810 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | 23S rRNA Um-2552 2'-O-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.704 |
| Ping_0809 | rplK | Ping_0809 | Ping_3450 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.861 |
| Ping_0809 | rsfS | Ping_0809 | Ping_1137 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.672 |
| Ping_0809 | rsmA | Ping_0809 | Ping_1047 | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.468 |
| Ping_0814 | Ping_0809 | Ping_0814 | Ping_0809 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | PFAM: protein of unknown function UPF0044; KEGG: pat:Patl_1569 protein of unknown function UPF0044. | 0.485 |
| Ping_0814 | infA | Ping_0814 | Ping_0744 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.696 |
| Ping_0814 | rlmE | Ping_0814 | Ping_0810 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 23S rRNA Um-2552 2'-O-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.518 |