STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ping_0995RNA polymerase, sigma-24 subunit, RpoE; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: vfi:VFA0766 RNA polymerase sigma-E factor homologue; Belongs to the sigma-70 factor family. ECF subfamily. (206 aa)    
Predicted Functional Partners:
Ping_0996
TIGRFAM: anti-sigma factor, putative, ChrR family; KEGG: son:SO1985 transcriptional activator, putative.
 
 
 0.987
Ping_0066
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
 
 0.918
Ping_0997
PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: son:SO3386 hypothetical protein.
  
  
 0.783
Ping_1001
PFAM: amine oxidase; KEGG: vfi:VFA0762 putative dehydrogenase.
 
  
 0.775
Ping_0994
SMART: peptidase S16, lon domain protein; KEGG: son:SO1987 ATP-dependent protease La (LON) domain protein.
 
   
 0.767
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.762
Ping_1002
PFAM: protein of unknown function DUF1365; KEGG: vfi:VFA0761 plasmid partition ParA protein.
 
     0.761
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.750
Ping_1000
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: pha:PSHAb0455 hypothetical protein.
 
     0.716
Ping_0999
KEGG: vfi:VFA0764 hypothetical transcriptional regulatory protein.
 
   
 0.709
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
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