| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0113 | Ping_1010 | Ping_0113 | Ping_1010 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: psb:Psyr_3988 hypothetical protein. | 0.457 |
| Ping_0113 | cysG | Ping_0113 | Ping_0298 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.746 |
| Ping_1007 | Ping_1009 | Ping_1007 | Ping_1009 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | Transporter, NhaC family; PFAM: Na+/H+ antiporter NhaC; KEGG: vfi:VF1630 Na(+)/H(+) antiporter; TC 2.A.35. | 0.481 |
| Ping_1007 | Ping_1010 | Ping_1007 | Ping_1010 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | KEGG: psb:Psyr_3988 hypothetical protein. | 0.559 |
| Ping_1007 | cysG | Ping_1007 | Ping_0298 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.543 |
| Ping_1009 | Ping_1007 | Ping_1009 | Ping_1007 | Transporter, NhaC family; PFAM: Na+/H+ antiporter NhaC; KEGG: vfi:VF1630 Na(+)/H(+) antiporter; TC 2.A.35. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | 0.481 |
| Ping_1009 | Ping_1010 | Ping_1009 | Ping_1010 | Transporter, NhaC family; PFAM: Na+/H+ antiporter NhaC; KEGG: vfi:VF1630 Na(+)/H(+) antiporter; TC 2.A.35. | KEGG: psb:Psyr_3988 hypothetical protein. | 0.443 |
| Ping_1010 | Ping_0113 | Ping_1010 | Ping_0113 | KEGG: psb:Psyr_3988 hypothetical protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.457 |
| Ping_1010 | Ping_1007 | Ping_1010 | Ping_1007 | KEGG: psb:Psyr_3988 hypothetical protein. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | 0.559 |
| Ping_1010 | Ping_1009 | Ping_1010 | Ping_1009 | KEGG: psb:Psyr_3988 hypothetical protein. | Transporter, NhaC family; PFAM: Na+/H+ antiporter NhaC; KEGG: vfi:VF1630 Na(+)/H(+) antiporter; TC 2.A.35. | 0.443 |
| Ping_1010 | cysG | Ping_1010 | Ping_0298 | KEGG: psb:Psyr_3988 hypothetical protein. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.612 |
| cysG | Ping_0113 | Ping_0298 | Ping_0113 | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.746 |
| cysG | Ping_1007 | Ping_0298 | Ping_1007 | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | 0.543 |
| cysG | Ping_1010 | Ping_0298 | Ping_1010 | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | KEGG: psb:Psyr_3988 hypothetical protein. | 0.612 |