| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apaH | pdxA | Ping_1046 | Ping_1048 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.745 |
| apaH | rsmA | Ping_1046 | Ping_1047 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.882 |
| apaH | surA | Ping_1046 | Ping_1049 | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | PpiC-type peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.786 |
| era | rimP | Ping_0641 | Ping_0815 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Hypothetical protein DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.508 |
| era | rpsE | Ping_0641 | Ping_3507 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.670 |
| era | rpsG | Ping_0641 | Ping_3439 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.803 |
| era | rpsI | Ping_0641 | Ping_2876 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | PFAM: ribosomal protein S9; KEGG: sgl:SG0217 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.765 |
| era | rpsL | Ping_0641 | Ping_3440 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. | 0.683 |
| era | rpsO | Ping_0641 | Ping_0824 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.728 |
| era | rsmA | Ping_0641 | Ping_1047 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.863 |
| pdxA | apaH | Ping_1048 | Ping_1046 | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.745 |
| pdxA | rsmA | Ping_1048 | Ping_1047 | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.929 |
| pdxA | surA | Ping_1048 | Ping_1049 | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | PpiC-type peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. | 0.856 |
| rimP | era | Ping_0815 | Ping_0641 | Hypothetical protein DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.508 |
| rimP | rpsE | Ping_0815 | Ping_3507 | Hypothetical protein DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.839 |
| rimP | rpsG | Ping_0815 | Ping_3439 | Hypothetical protein DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.906 |
| rimP | rpsI | Ping_0815 | Ping_2876 | Hypothetical protein DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | PFAM: ribosomal protein S9; KEGG: sgl:SG0217 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.886 |
| rimP | rpsL | Ping_0815 | Ping_3440 | Hypothetical protein DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. | 0.955 |
| rimP | rpsO | Ping_0815 | Ping_0824 | Hypothetical protein DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.896 |
| rimP | rsmA | Ping_0815 | Ping_1047 | Hypothetical protein DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.864 |