STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ping_1081PFAM: Uncharacterized lipoprotein; KEGG: cps:CPS_0710 putative lipoprotein. (197 aa)    
Predicted Functional Partners:
Ping_0875
PFAM: CopG domain protein DNA-binding domain protein; KEGG: cps:CPS_1577 hypothetical protein.
  
    0.774
Ping_0347
Acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: vfi:VF2557 acetolactate synthase small subunit.
  
     0.773
Ping_1986
PFAM: protein of unknown function UPF0227; KEGG: vfi:VF1142 hypothetical protein.
  
     0.763
Ping_0666
PFAM: porin, Gram-negative type; KEGG: vpa:VPA0527 outer membrane protein N, non-specific porin.
  
     0.735
Ping_2268
PFAM: protein of unknown function DUF1414; KEGG: pha:PSHAa1818 hypothetical protein; Belongs to the UPF0352 family.
  
    0.731
Ping_1080
Peptidyl-prolyl cis-trans isomerase, cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
    0.722
Ping_3613
PFAM: porin, Gram-negative type; KEGG: vvu:VV20580 outer membrane protein.
  
     0.714
seqA
Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
    0.699
priB
Restart primosome assembly protein PriB; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
  
    0.698
Ping_0066
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
     0.697
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
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