| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0739 | Ping_0740 | Ping_0739 | Ping_0740 | Hypothetical protein. | Ribonucleoside-triphosphate reductase class III catalytic subunit; KEGG: sec:SC4307 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | 0.586 |
| Ping_0739 | queE | Ping_0739 | Ping_1100 | Hypothetical protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.707 |
| Ping_0740 | Ping_0739 | Ping_0740 | Ping_0739 | Ribonucleoside-triphosphate reductase class III catalytic subunit; KEGG: sec:SC4307 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | Hypothetical protein. | 0.586 |
| Ping_0740 | queE | Ping_0740 | Ping_1100 | Ribonucleoside-triphosphate reductase class III catalytic subunit; KEGG: sec:SC4307 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.707 |
| Ping_2266 | guaA | Ping_2266 | Ping_2949 | KEGG: pat:Patl_3377 hypothetical protein. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.450 |
| Ping_2266 | queC | Ping_2266 | Ping_1099 | KEGG: pat:Patl_3377 hypothetical protein. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.922 |
| Ping_2266 | queE | Ping_2266 | Ping_1100 | KEGG: pat:Patl_3377 hypothetical protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.790 |
| Ping_2266 | queF | Ping_2266 | Ping_2773 | KEGG: pat:Patl_3377 hypothetical protein. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.844 |
| Ping_3310 | queE | Ping_3310 | Ping_1100 | PFAM: protein of unknown function DUF412; KEGG: yps:YPTB2595 hypothetical protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.456 |
| Ping_3310 | rraB | Ping_3310 | Ping_0862 | PFAM: protein of unknown function DUF412; KEGG: yps:YPTB2595 hypothetical protein. | Hypothetical protein DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.775 |
| Ping_3310 | syd | Ping_3310 | Ping_2772 | PFAM: protein of unknown function DUF412; KEGG: yps:YPTB2595 hypothetical protein. | Syd family protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.770 |
| guaA | Ping_2266 | Ping_2949 | Ping_2266 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | KEGG: pat:Patl_3377 hypothetical protein. | 0.450 |
| guaA | queE | Ping_2949 | Ping_1100 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.451 |
| guaA | queF | Ping_2949 | Ping_2773 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.576 |
| nadA | queE | Ping_0730 | Ping_1100 | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.465 |
| queC | Ping_2266 | Ping_1099 | Ping_2266 | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | KEGG: pat:Patl_3377 hypothetical protein. | 0.922 |
| queC | queE | Ping_1099 | Ping_1100 | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.996 |
| queC | queF | Ping_1099 | Ping_2773 | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.983 |
| queE | Ping_0739 | Ping_1100 | Ping_0739 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Hypothetical protein. | 0.707 |
| queE | Ping_0740 | Ping_1100 | Ping_0740 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Ribonucleoside-triphosphate reductase class III catalytic subunit; KEGG: sec:SC4307 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | 0.707 |