| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_2256 | Ping_2371 | Ping_2256 | Ping_2371 | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: vfi:VF0819 succinate dehydrogenase cytochrome b556 subunit. | KEGG: vch:VCA0432 hypothetical protein. | 0.479 |
| Ping_2256 | napF | Ping_2256 | Ping_2176 | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: vfi:VF0819 succinate dehydrogenase cytochrome b556 subunit. | Periplasmic nitrate reductase maturation protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family. | 0.883 |
| Ping_2371 | Ping_2256 | Ping_2371 | Ping_2256 | KEGG: vch:VCA0432 hypothetical protein. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: vfi:VF0819 succinate dehydrogenase cytochrome b556 subunit. | 0.479 |
| Ping_2371 | Ping_2607 | Ping_2371 | Ping_2607 | KEGG: vch:VCA0432 hypothetical protein. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.501 |
| Ping_2371 | Ping_3347 | Ping_2371 | Ping_3347 | KEGG: vch:VCA0432 hypothetical protein. | PFAM: SapC family protein; KEGG: sil:SPO2717 SapC protein, putative. | 0.444 |
| Ping_2371 | birA | Ping_2371 | Ping_0219 | KEGG: vch:VCA0432 hypothetical protein. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.443 |
| Ping_2371 | napF | Ping_2371 | Ping_2176 | KEGG: vch:VCA0432 hypothetical protein. | Periplasmic nitrate reductase maturation protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family. | 0.550 |
| Ping_2371 | thiE-2 | Ping_2371 | Ping_2372 | KEGG: vch:VCA0432 hypothetical protein. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.503 |
| Ping_2371 | thiM | Ping_2371 | Ping_2373 | KEGG: vch:VCA0432 hypothetical protein. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.425 |
| Ping_2607 | Ping_2371 | Ping_2607 | Ping_2371 | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | KEGG: vch:VCA0432 hypothetical protein. | 0.501 |
| Ping_2607 | birA | Ping_2607 | Ping_0219 | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.726 |
| Ping_3347 | Ping_2371 | Ping_3347 | Ping_2371 | PFAM: SapC family protein; KEGG: sil:SPO2717 SapC protein, putative. | KEGG: vch:VCA0432 hypothetical protein. | 0.444 |
| birA | Ping_2371 | Ping_0219 | Ping_2371 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | KEGG: vch:VCA0432 hypothetical protein. | 0.443 |
| birA | Ping_2607 | Ping_0219 | Ping_2607 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.726 |
| napF | Ping_2256 | Ping_2176 | Ping_2256 | Periplasmic nitrate reductase maturation protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: vfi:VF0819 succinate dehydrogenase cytochrome b556 subunit. | 0.883 |
| napF | Ping_2371 | Ping_2176 | Ping_2371 | Periplasmic nitrate reductase maturation protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family. | KEGG: vch:VCA0432 hypothetical protein. | 0.550 |
| thiE-2 | Ping_2371 | Ping_2372 | Ping_2371 | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | KEGG: vch:VCA0432 hypothetical protein. | 0.503 |
| thiE-2 | thiM | Ping_2372 | Ping_2373 | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.999 |
| thiM | Ping_2371 | Ping_2373 | Ping_2371 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | KEGG: vch:VCA0432 hypothetical protein. | 0.425 |
| thiM | thiE-2 | Ping_2373 | Ping_2372 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |