node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ping_0074 | Ping_3391 | Ping_0074 | Ping_3391 | PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: pha:PSHAa0027 DNA topoisomerase. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.544 |
Ping_0074 | polA | Ping_0074 | Ping_3185 | PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: pha:PSHAa0027 DNA topoisomerase. | Fused DNA polymerase 5'->3' exonuclease and 3'->5' polymerase and 3'->5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.434 |
Ping_0074 | topB | Ping_0074 | Ping_2461 | PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: pha:PSHAa0027 DNA topoisomerase. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.859 |
Ping_0199 | Ping_1095 | Ping_0199 | Ping_1095 | KEGG: vvy:VV3187 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: sdy:SDY_2051 DNA polymerase III, delta prime subunit. | 0.653 |
Ping_0199 | Ping_1303 | Ping_0199 | Ping_1303 | KEGG: vvy:VV3187 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | PFAM: SMC domain protein; KEGG: yps:YPTB0915 putative ATP-dependent dsDNA exonuclease. | 0.895 |
Ping_0199 | Ping_3396 | Ping_0199 | Ping_3396 | KEGG: vvy:VV3187 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | KEGG: psb:Psyr_4948 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.921 |
Ping_0199 | polA | Ping_0199 | Ping_3185 | KEGG: vvy:VV3187 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | Fused DNA polymerase 5'->3' exonuclease and 3'->5' polymerase and 3'->5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.955 |
Ping_0199 | recA | Ping_0199 | Ping_3381 | KEGG: vvy:VV3187 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.926 |
Ping_0199 | sbcD | Ping_0199 | Ping_1302 | KEGG: vvy:VV3187 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.937 |
Ping_0199 | topB | Ping_0199 | Ping_2461 | KEGG: vvy:VV3187 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.977 |
Ping_1007 | Ping_3391 | Ping_1007 | Ping_3391 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.466 |
Ping_1007 | polA | Ping_1007 | Ping_3185 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | Fused DNA polymerase 5'->3' exonuclease and 3'->5' polymerase and 3'->5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.539 |
Ping_1007 | recA | Ping_1007 | Ping_3381 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.457 |
Ping_1007 | topB | Ping_1007 | Ping_2461 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.684 |
Ping_1095 | Ping_0199 | Ping_1095 | Ping_0199 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: sdy:SDY_2051 DNA polymerase III, delta prime subunit. | KEGG: vvy:VV3187 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.653 |
Ping_1095 | Ping_1303 | Ping_1095 | Ping_1303 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: sdy:SDY_2051 DNA polymerase III, delta prime subunit. | PFAM: SMC domain protein; KEGG: yps:YPTB0915 putative ATP-dependent dsDNA exonuclease. | 0.706 |
Ping_1095 | Ping_3396 | Ping_1095 | Ping_3396 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: sdy:SDY_2051 DNA polymerase III, delta prime subunit. | KEGG: psb:Psyr_4948 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.653 |
Ping_1095 | polA | Ping_1095 | Ping_3185 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: sdy:SDY_2051 DNA polymerase III, delta prime subunit. | Fused DNA polymerase 5'->3' exonuclease and 3'->5' polymerase and 3'->5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.910 |
Ping_1095 | recA | Ping_1095 | Ping_3381 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: sdy:SDY_2051 DNA polymerase III, delta prime subunit. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.866 |
Ping_1095 | sbcD | Ping_1095 | Ping_1302 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: sdy:SDY_2051 DNA polymerase III, delta prime subunit. | Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.773 |