STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ping_2499PFAM: heat shock protein DnaJ domain protein; KEGG: hch:HCH_06092 DnaJ-class molecular chaperone. (253 aa)    
Predicted Functional Partners:
Ping_1217
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit.
   
  0.925
Ping_2498
KEGG: hch:HCH_06093 hypothetical protein.
 
     0.905
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
 
 0.873
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
 
 0.805
Ping_0515
KEGG: pat:Patl_2983 putative heat shock protein 70 family protein.
  
 0.679
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.679
Ping_1232
Chaperone DnaK-related protein; KEGG: hch:HCH_03650 molecular chaperone; Belongs to the heat shock protein 70 family.
  
 0.679
Ping_1233
Chaperone DnaK-related protein; KEGG: hch:HCH_03649 molecular chaperone.
  
 0.679
hscA
Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
  
 0.679
Ping_2692
PFAM: Heat shock protein 70; KEGG: bth:BT4602 chaperone protein DnaK.
  
 0.679
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.