| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0113 | Ping_2607 | Ping_0113 | Ping_2607 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.625 |
| Ping_0169 | Ping_2607 | Ping_0169 | Ping_2607 | KEGG: eca:ECA1929 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.501 |
| Ping_0169 | birA | Ping_0169 | Ping_0219 | KEGG: eca:ECA1929 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.443 |
| Ping_0189 | Ping_2607 | Ping_0189 | Ping_2607 | O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_3770 O-succinylbenzoate-CoA ligase. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.551 |
| Ping_0574 | Ping_2607 | Ping_0574 | Ping_2607 | PFAM: ABC-2 type transporter; KEGG: vfi:VF2171 ABC transporter permease protein. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.793 |
| Ping_1007 | Ping_2607 | Ping_1007 | Ping_2607 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.551 |
| Ping_1014 | Ping_2607 | Ping_1014 | Ping_2607 | PFAM: AMP-dependent synthetase and ligase; KEGG: ype:YPO2074 long-chain-fatty-acid-CoA ligase. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.551 |
| Ping_1534 | Ping_1902 | Ping_1534 | Ping_1902 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: mma:MM3105 putative cytosine deaminase. | PFAM: Inosine/uridine-preferring nucleoside hydrolase; Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: psp:PSPPH_2471 inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. | 0.664 |
| Ping_1534 | Ping_2607 | Ping_1534 | Ping_2607 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: mma:MM3105 putative cytosine deaminase. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.685 |
| Ping_1534 | birA | Ping_1534 | Ping_0219 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: mma:MM3105 putative cytosine deaminase. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.813 |
| Ping_1902 | Ping_1534 | Ping_1902 | Ping_1534 | PFAM: Inosine/uridine-preferring nucleoside hydrolase; Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: psp:PSPPH_2471 inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: mma:MM3105 putative cytosine deaminase. | 0.664 |
| Ping_1902 | Ping_2607 | Ping_1902 | Ping_2607 | PFAM: Inosine/uridine-preferring nucleoside hydrolase; Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: psp:PSPPH_2471 inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.656 |
| Ping_1902 | birA | Ping_1902 | Ping_0219 | PFAM: Inosine/uridine-preferring nucleoside hydrolase; Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: psp:PSPPH_2471 inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.496 |
| Ping_1999 | Ping_2607 | Ping_1999 | Ping_2607 | PFAM: AMP-dependent synthetase and ligase; KEGG: ppr:PBPRA1464 peptide synthase. | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | 0.551 |
| Ping_2607 | Ping_0113 | Ping_2607 | Ping_0113 | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.625 |
| Ping_2607 | Ping_0169 | Ping_2607 | Ping_0169 | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | KEGG: eca:ECA1929 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. | 0.501 |
| Ping_2607 | Ping_0189 | Ping_2607 | Ping_0189 | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_3770 O-succinylbenzoate-CoA ligase. | 0.551 |
| Ping_2607 | Ping_0574 | Ping_2607 | Ping_0574 | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | PFAM: ABC-2 type transporter; KEGG: vfi:VF2171 ABC transporter permease protein. | 0.793 |
| Ping_2607 | Ping_1007 | Ping_2607 | Ping_1007 | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | 0.551 |
| Ping_2607 | Ping_1014 | Ping_2607 | Ping_1014 | PFAM: nitroreductase; KEGG: csa:Csal_0202 nitroreductase; Belongs to the flavin oxidoreductase frp family. | PFAM: AMP-dependent synthetase and ligase; KEGG: ype:YPO2074 long-chain-fatty-acid-CoA ligase. | 0.551 |