STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ping_2880DegS peptidase, Serine peptidase, MEROPS family S01B; TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: vvu:VV10604 protease DegS. (368 aa)    
Predicted Functional Partners:
Ping_0066
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
 
 0.901
Ping_0690
PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: ppr:PBPRB0642 hypothetical outer membrane protein OmpA; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 
 0.864
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.767
Ping_3719
Sensor histidine kinase with ATPase domain; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: vvy:VVA0933 signal transduction histidine kinase.
  
  
 0.631
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.587
pspC
PFAM: PspC domain protein; KEGG: ppr:PBPRA2437 hypothetical phage shock protein C.
  
  
 0.575
rpsP
PFAM: ribosomal protein S16; KEGG: cps:CPS_4069 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
 
   0.571
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.558
Ping_2969
Site-2 protease, Metallo peptidase, MEROPS family M50B; TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: sdn:Sden_1561 peptidase M50, putative membrane-associated zinc metallopeptidase.
 
  
 0.556
rpsI
PFAM: ribosomal protein S9; KEGG: sgl:SG0217 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
   0.548
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
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