STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ping_2880DegS peptidase, Serine peptidase, MEROPS family S01B; TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: vvu:VV10604 protease DegS. (368 aa)    
Predicted Functional Partners:
Ping_0690
PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: ppr:PBPRB0642 hypothetical outer membrane protein OmpA; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 
 0.920
Ping_0066
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
 
 0.869
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.753
Ping_3480
Pitrilysin, Metallo peptidase, MEROPS family M16A; PFAM: peptidase M16 domain protein; KEGG: pha:PSHAb0349 putative TonB-dependent receptor protease/peptidase.
  
 
 0.706
Ping_3719
Sensor histidine kinase with ATPase domain; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: vvy:VVA0933 signal transduction histidine kinase.
  
  
 0.656
paaN
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: aldehyde dehydrogenase; MaoC domain protein dehydratase; KEGG: ecj:JW1382 fused aldehyde dehydrogenase and enoyl-CoA hydratase.
   
 0.645
Ping_2603
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: mbo:Mb0897 probable acyl-CoA dehydrogenase FadE10.
    
  0.644
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
  0.639
Ping_3008
PFAM: MaoC domain protein dehydratase; KEGG: ppr:PBPRB0808 hypothetical acyl dehydratase.
    
  0.618
pspC
PFAM: PspC domain protein; KEGG: ppr:PBPRA2437 hypothetical phage shock protein C.
  
  
 0.534
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.