STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureCUrease, Metallo peptidase, MEROPS family M38; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Amidohydrolase 3; KEGG: hch:HCH_04523 urease, alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (567 aa)    
Predicted Functional Partners:
ureA
Urease, gamma subunit; KEGG: hch:HCH_04521 UreA amidohydrolase (urease) gamma subunit; TIGRFAM: urease, gamma subunit; PFAM: Urease, gamma subunit region; Belongs to the urease gamma subunit family.
 0.999
ureB
KEGG: pen:PSEEN2095 urease, beta subunit; TIGRFAM: urease, beta subunit; PFAM: Urease, beta subunit; Belongs to the urease beta subunit family.
 0.999
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 0.987
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.986
ureE
UreE urease accessory domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.964
Ping_0417
PFAM: Amidase; KEGG: mlo:mlr7070 glutamyl-tRNA(Gln) amidotransferase subunit A.
     
  0.900
Ping_2417
Allophanate hydrolase; PFAM: Amidase; KEGG: rpa:RPA1404 glutamyl-tRNA(Gln) amidotransferase subunit A.
     
  0.900
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.840
hypB
GTP hydrolase, accessory liganding Ni into hydrogenases, HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: rfr:Rfer_4096 hydrogenase accessory protein HypB.
  
  
 0.684
Ping_2990
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: abo:ABO_2513 amino acid ABC transporter, ATP-binding protein; TC 3.A.1.4.-.
     
 0.550
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
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