| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0497 | Ping_3042 | Ping_0497 | Ping_3042 | PFAM: Methyltransferase type 11; KEGG: pha:PSHAa1965 S-adenosyl-L-methionine-dependent methyltransferase. | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | 0.531 |
| Ping_3040 | Ping_3042 | Ping_3040 | Ping_3042 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | 0.844 |
| Ping_3040 | Ping_3043 | Ping_3040 | Ping_3043 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | 0.532 |
| Ping_3040 | Ping_3044 | Ping_3040 | Ping_3044 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | KEGG: vfi:VF0426 hypothetical protein. | 0.510 |
| Ping_3040 | Ping_3045 | Ping_3040 | Ping_3045 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.658 |
| Ping_3040 | Ping_3046 | Ping_3040 | Ping_3046 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.658 |
| Ping_3040 | proC | Ping_3040 | Ping_3041 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.908 |
| Ping_3042 | Ping_0497 | Ping_3042 | Ping_0497 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | PFAM: Methyltransferase type 11; KEGG: pha:PSHAa1965 S-adenosyl-L-methionine-dependent methyltransferase. | 0.531 |
| Ping_3042 | Ping_3040 | Ping_3042 | Ping_3040 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.844 |
| Ping_3042 | Ping_3043 | Ping_3042 | Ping_3043 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | 0.844 |
| Ping_3042 | Ping_3044 | Ping_3042 | Ping_3044 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | KEGG: vfi:VF0426 hypothetical protein. | 0.785 |
| Ping_3042 | Ping_3045 | Ping_3042 | Ping_3045 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.729 |
| Ping_3042 | Ping_3046 | Ping_3042 | Ping_3046 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.594 |
| Ping_3042 | ftsL | Ping_3042 | Ping_1140 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.516 |
| Ping_3042 | ftsZ | Ping_3042 | Ping_1152 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.614 |
| Ping_3042 | proC | Ping_3042 | Ping_3041 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.812 |
| Ping_3042 | rnfH | Ping_3042 | Ping_1604 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | PFAM: protein of unknown function UPF0125; KEGG: cps:CPS_3827 hypothetical protein; Belongs to the UPF0125 (RnfH) family. | 0.587 |
| Ping_3043 | Ping_3040 | Ping_3043 | Ping_3040 | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.532 |
| Ping_3043 | Ping_3042 | Ping_3043 | Ping_3042 | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | 0.844 |
| Ping_3043 | Ping_3044 | Ping_3043 | Ping_3044 | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | KEGG: vfi:VF0426 hypothetical protein. | 0.742 |