node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ping_3040 | Ping_3042 | Ping_3040 | Ping_3042 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | 0.777 |
Ping_3040 | Ping_3043 | Ping_3040 | Ping_3043 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | 0.512 |
Ping_3040 | Ping_3044 | Ping_3040 | Ping_3044 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | KEGG: vfi:VF0426 hypothetical protein. | 0.430 |
Ping_3040 | Ping_3045 | Ping_3040 | Ping_3045 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.615 |
Ping_3040 | Ping_3046 | Ping_3040 | Ping_3046 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.603 |
Ping_3040 | proC | Ping_3040 | Ping_3041 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.895 |
Ping_3042 | Ping_3040 | Ping_3042 | Ping_3040 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.777 |
Ping_3042 | Ping_3043 | Ping_3042 | Ping_3043 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | 0.834 |
Ping_3042 | Ping_3044 | Ping_3042 | Ping_3044 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | KEGG: vfi:VF0426 hypothetical protein. | 0.752 |
Ping_3042 | Ping_3045 | Ping_3042 | Ping_3045 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.674 |
Ping_3042 | Ping_3046 | Ping_3042 | Ping_3046 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.529 |
Ping_3042 | proC | Ping_3042 | Ping_3041 | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.768 |
Ping_3043 | Ping_3040 | Ping_3043 | Ping_3040 | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.512 |
Ping_3043 | Ping_3042 | Ping_3043 | Ping_3042 | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | 0.834 |
Ping_3043 | Ping_3044 | Ping_3043 | Ping_3044 | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | KEGG: vfi:VF0426 hypothetical protein. | 0.736 |
Ping_3043 | Ping_3045 | Ping_3043 | Ping_3045 | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.643 |
Ping_3043 | Ping_3046 | Ping_3043 | Ping_3046 | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.499 |
Ping_3043 | proC | Ping_3043 | Ping_3041 | PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.694 |
Ping_3044 | Ping_3040 | Ping_3044 | Ping_3040 | KEGG: vfi:VF0426 hypothetical protein. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.430 |
Ping_3044 | Ping_3042 | Ping_3044 | Ping_3042 | KEGG: vfi:VF0426 hypothetical protein. | PFAM: protein of unknown function YGGT; KEGG: vvu:VV11523 predicted integral membrane protein. | 0.752 |