| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0113 | Ping_1275 | Ping_0113 | Ping_1275 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate kinase; KEGG: vfi:VF2118 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.975 |
| Ping_0113 | Ping_1993 | Ping_0113 | Ping_1993 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: vch:VC2107 aspartate-semialdehyde dehydrogenase, putative. | 0.593 |
| Ping_0113 | Ping_3379 | Ping_0113 | Ping_3379 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate kinase; KEGG: hch:HCH_05208 asparate kinase, monofunctional class; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.642 |
| Ping_0113 | argH | Ping_0113 | Ping_0232 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Argininosuccinate lyase / N-acetylglutamate synthase; TIGRFAM: argininosuccinate lyase; PFAM: GCN5-related N-acetyltransferase; fumarate lyase; KEGG: vpa:VP2756 argininosuccinase and n-acetylglutamate synthase; In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | 0.758 |
| Ping_0113 | asd | Ping_0113 | Ping_3206 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.593 |
| Ping_0113 | thrB | Ping_0113 | Ping_1276 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.923 |
| Ping_1007 | Ping_1275 | Ping_1007 | Ping_1275 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | Aspartate kinase; KEGG: vfi:VF2118 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.816 |
| Ping_1007 | Ping_1993 | Ping_1007 | Ping_1993 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: vch:VC2107 aspartate-semialdehyde dehydrogenase, putative. | 0.691 |
| Ping_1007 | Ping_2287 | Ping_1007 | Ping_2287 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | TIGRFAM: 2,4-diaminobutyrate 4-transaminase; PFAM: aminotransferase class-III; KEGG: ppr:PBPRA2230 putative diaminobutyrate-pyruvate transaminase & L-2,4-diaminobutyrate decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.542 |
| Ping_1007 | Ping_3379 | Ping_1007 | Ping_3379 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | Aspartate kinase; KEGG: hch:HCH_05208 asparate kinase, monofunctional class; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.431 |
| Ping_1007 | argH | Ping_1007 | Ping_0232 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | Argininosuccinate lyase / N-acetylglutamate synthase; TIGRFAM: argininosuccinate lyase; PFAM: GCN5-related N-acetyltransferase; fumarate lyase; KEGG: vpa:VP2756 argininosuccinase and n-acetylglutamate synthase; In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | 0.760 |
| Ping_1007 | asd | Ping_1007 | Ping_3206 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.691 |
| Ping_1007 | guaA | Ping_1007 | Ping_2949 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.775 |
| Ping_1007 | thrB | Ping_1007 | Ping_1276 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.614 |
| Ping_1275 | Ping_0113 | Ping_1275 | Ping_0113 | Aspartate kinase; KEGG: vfi:VF2118 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.975 |
| Ping_1275 | Ping_1007 | Ping_1275 | Ping_1007 | Aspartate kinase; KEGG: vfi:VF2118 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ppr:PBPRA0542 putative glutamate synthase, large subunit. | 0.816 |
| Ping_1275 | Ping_1993 | Ping_1275 | Ping_1993 | Aspartate kinase; KEGG: vfi:VF2118 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: vch:VC2107 aspartate-semialdehyde dehydrogenase, putative. | 0.990 |
| Ping_1275 | Ping_2287 | Ping_1275 | Ping_2287 | Aspartate kinase; KEGG: vfi:VF2118 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | TIGRFAM: 2,4-diaminobutyrate 4-transaminase; PFAM: aminotransferase class-III; KEGG: ppr:PBPRA2230 putative diaminobutyrate-pyruvate transaminase & L-2,4-diaminobutyrate decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.929 |
| Ping_1275 | Ping_3379 | Ping_1275 | Ping_3379 | Aspartate kinase; KEGG: vfi:VF2118 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Aspartate kinase; KEGG: hch:HCH_05208 asparate kinase, monofunctional class; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.976 |
| Ping_1275 | argH | Ping_1275 | Ping_0232 | Aspartate kinase; KEGG: vfi:VF2118 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Argininosuccinate lyase / N-acetylglutamate synthase; TIGRFAM: argininosuccinate lyase; PFAM: GCN5-related N-acetyltransferase; fumarate lyase; KEGG: vpa:VP2756 argininosuccinase and n-acetylglutamate synthase; In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | 0.785 |