| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0871 | Ping_3209 | Ping_0871 | Ping_3209 | PFAM: Rhodanese domain protein; KEGG: cps:CPS_3148 putative phage shock protein E. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.521 |
| Ping_1112 | Ping_3209 | Ping_1112 | Ping_3209 | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.901 |
| Ping_2449 | Ping_3209 | Ping_2449 | Ping_3209 | TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: vpa:VP2117 putative glutaredoxin protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.693 |
| Ping_2449 | nfuA | Ping_2449 | Ping_3202 | TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: vpa:VP2117 putative glutaredoxin protein; Belongs to the glutaredoxin family. Monothiol subfamily. | HesB/YadR/YfhF-family protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.856 |
| Ping_2628 | Ping_3209 | Ping_2628 | Ping_3209 | Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.568 |
| Ping_2628 | queF | Ping_2628 | Ping_2773 | Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.771 |
| Ping_3209 | Ping_0871 | Ping_3209 | Ping_0871 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | PFAM: Rhodanese domain protein; KEGG: cps:CPS_3148 putative phage shock protein E. | 0.521 |
| Ping_3209 | Ping_1112 | Ping_3209 | Ping_1112 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.901 |
| Ping_3209 | Ping_2449 | Ping_3209 | Ping_2449 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: vpa:VP2117 putative glutaredoxin protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.693 |
| Ping_3209 | Ping_2628 | Ping_3209 | Ping_2628 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 0.568 |
| Ping_3209 | Ping_3210 | Ping_3209 | Ping_3210 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | PFAM: Rhodanese domain protein; KEGG: eca:ECA0171 putative rhodanese-related sulfurtransferase. | 0.893 |
| Ping_3209 | atpF-2 | Ping_3209 | Ping_3734 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | ATP synthase F0 subcomplex B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.640 |
| Ping_3209 | gpsA | Ping_3209 | Ping_3207 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; KEGG: son:SO0053 glycerol-3-phosphate dehydrogenase (NAD(P)+). | 0.546 |
| Ping_3209 | nfuA | Ping_3209 | Ping_3202 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | HesB/YadR/YfhF-family protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.536 |
| Ping_3209 | queF | Ping_3209 | Ping_2773 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.474 |
| Ping_3209 | secB | Ping_3209 | Ping_3208 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.947 |
| Ping_3210 | Ping_3209 | Ping_3210 | Ping_3209 | PFAM: Rhodanese domain protein; KEGG: eca:ECA0171 putative rhodanese-related sulfurtransferase. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.893 |
| Ping_3210 | gpsA | Ping_3210 | Ping_3207 | PFAM: Rhodanese domain protein; KEGG: eca:ECA0171 putative rhodanese-related sulfurtransferase. | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; KEGG: son:SO0053 glycerol-3-phosphate dehydrogenase (NAD(P)+). | 0.432 |
| Ping_3210 | secB | Ping_3210 | Ping_3208 | PFAM: Rhodanese domain protein; KEGG: eca:ECA0171 putative rhodanese-related sulfurtransferase. | Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.633 |
| atpF-2 | Ping_3209 | Ping_3734 | Ping_3209 | ATP synthase F0 subcomplex B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.640 |