| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0029 | Ping_3241 | Ping_0029 | Ping_3241 | PFAM: pentapeptide repeat protein; KEGG: bbr:BB0795 hypothetical protein. | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | 0.892 |
| Ping_3241 | Ping_0029 | Ping_3241 | Ping_0029 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | PFAM: pentapeptide repeat protein; KEGG: bbr:BB0795 hypothetical protein. | 0.892 |
| Ping_3241 | Ping_3242 | Ping_3241 | Ping_3242 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | 0.866 |
| Ping_3241 | ftsA | Ping_3241 | Ping_1151 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.786 |
| Ping_3241 | guaA | Ping_3241 | Ping_2949 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.740 |
| Ping_3241 | lolA | Ping_3241 | Ping_1663 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.858 |
| Ping_3241 | miaA | Ping_3241 | Ping_3239 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.918 |
| Ping_3241 | mltF | Ping_3241 | Ping_3319 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | Lytic transglycosylase, catalytic; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. | 0.806 |
| Ping_3241 | mutL | Ping_3241 | Ping_3240 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.905 |
| Ping_3241 | nnrE | Ping_3241 | Ping_3243 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.902 |
| Ping_3241 | rlpA | Ping_3241 | Ping_1133 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.736 |
| Ping_3242 | Ping_3241 | Ping_3242 | Ping_3241 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | 0.866 |
| Ping_3242 | miaA | Ping_3242 | Ping_3239 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.888 |
| Ping_3242 | mutL | Ping_3242 | Ping_3240 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.812 |
| Ping_3242 | nnrE | Ping_3242 | Ping_3243 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.949 |
| ftsA | Ping_3241 | Ping_1151 | Ping_3241 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | 0.786 |
| ftsA | rlpA | Ping_1151 | Ping_1133 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.557 |
| guaA | Ping_3241 | Ping_2949 | Ping_3241 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | 0.740 |
| guaA | miaA | Ping_2949 | Ping_3239 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.542 |
| guaA | mltF | Ping_2949 | Ping_3319 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Lytic transglycosylase, catalytic; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. | 0.441 |