| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_1062 | Ping_2301 | Ping_1062 | Ping_2301 | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: vch:VC1178 hypothetical protein; Belongs to the SUA5 family. | PFAM: peptidase M22, glycoprotease; KEGG: pat:Patl_2808 peptidase M22, glycoprotease. | 0.646 |
| Ping_1062 | Ping_3242 | Ping_1062 | Ping_3242 | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: vch:VC1178 hypothetical protein; Belongs to the SUA5 family. | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | 0.640 |
| Ping_1062 | gcp | Ping_1062 | Ping_0314 | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: vch:VC1178 hypothetical protein; Belongs to the SUA5 family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.664 |
| Ping_2301 | Ping_1062 | Ping_2301 | Ping_1062 | PFAM: peptidase M22, glycoprotease; KEGG: pat:Patl_2808 peptidase M22, glycoprotease. | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: vch:VC1178 hypothetical protein; Belongs to the SUA5 family. | 0.646 |
| Ping_2301 | Ping_3242 | Ping_2301 | Ping_3242 | PFAM: peptidase M22, glycoprotease; KEGG: pat:Patl_2808 peptidase M22, glycoprotease. | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | 0.980 |
| Ping_2301 | gcp | Ping_2301 | Ping_0314 | PFAM: peptidase M22, glycoprotease; KEGG: pat:Patl_2808 peptidase M22, glycoprotease. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.993 |
| Ping_2301 | thiL | Ping_2301 | Ping_2241 | PFAM: peptidase M22, glycoprotease; KEGG: pat:Patl_2808 peptidase M22, glycoprotease. | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.494 |
| Ping_2301 | tsaC | Ping_2301 | Ping_0072 | PFAM: peptidase M22, glycoprotease; KEGG: pat:Patl_2808 peptidase M22, glycoprotease. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.688 |
| Ping_3241 | Ping_3242 | Ping_3241 | Ping_3242 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | 0.866 |
| Ping_3241 | miaA | Ping_3241 | Ping_3239 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.918 |
| Ping_3241 | mutL | Ping_3241 | Ping_3240 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.905 |
| Ping_3241 | nnrE | Ping_3241 | Ping_3243 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.902 |
| Ping_3241 | queG | Ping_3241 | Ping_3244 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | Putative iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.695 |
| Ping_3242 | Ping_1062 | Ping_3242 | Ping_1062 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: vch:VC1178 hypothetical protein; Belongs to the SUA5 family. | 0.640 |
| Ping_3242 | Ping_2301 | Ping_3242 | Ping_2301 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | PFAM: peptidase M22, glycoprotease; KEGG: pat:Patl_2808 peptidase M22, glycoprotease. | 0.980 |
| Ping_3242 | Ping_3241 | Ping_3242 | Ping_3241 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ppr:PBPRA3353 putative N-acetylmuramoyl-L-alanine amidase. | 0.866 |
| Ping_3242 | gcp | Ping_3242 | Ping_0314 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.905 |
| Ping_3242 | miaA | Ping_3242 | Ping_3239 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.888 |
| Ping_3242 | mutL | Ping_3242 | Ping_3240 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.812 |
| Ping_3242 | nnrE | Ping_3242 | Ping_3243 | PFAM: protein of unknown function UPF0079; KEGG: vvy:VV3075 predicted ATPase or kinase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.949 |