| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_1217 | Ping_2254 | Ping_1217 | Ping_2254 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit. | KEGG: vch:VC2089 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.952 |
| Ping_1217 | Ping_2255 | Ping_1217 | Ping_2255 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit. | Succinate dehydrogenase subunit D; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.645 |
| Ping_1217 | Ping_2256 | Ping_1217 | Ping_2256 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: vfi:VF0819 succinate dehydrogenase cytochrome b556 subunit. | 0.952 |
| Ping_1217 | Ping_3278 | Ping_1217 | Ping_3278 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit. | KEGG: vfi:VF2334 fumarate reductase flavoprotein subunit; TIGRFAM: fumarate reductase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.952 |
| Ping_1217 | Ping_3279 | Ping_1217 | Ping_3279 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit. | KEGG: cvi:CV3368 fumarate reductase, subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein. | 0.958 |
| Ping_1217 | sucC | Ping_1217 | Ping_2250 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.946 |
| Ping_1217 | sucD | Ping_1217 | Ping_2249 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.942 |
| Ping_1977 | Ping_2254 | Ping_1977 | Ping_2254 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | KEGG: vch:VC2089 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.991 |
| Ping_1977 | Ping_2255 | Ping_1977 | Ping_2255 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase subunit D; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.977 |
| Ping_1977 | Ping_2256 | Ping_1977 | Ping_2256 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: vfi:VF0819 succinate dehydrogenase cytochrome b556 subunit. | 0.974 |
| Ping_1977 | Ping_3278 | Ping_1977 | Ping_3278 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | KEGG: vfi:VF2334 fumarate reductase flavoprotein subunit; TIGRFAM: fumarate reductase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.991 |
| Ping_1977 | Ping_3279 | Ping_1977 | Ping_3279 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | KEGG: cvi:CV3368 fumarate reductase, subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein. | 0.983 |
| Ping_1977 | Ping_3280 | Ping_1977 | Ping_3280 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: fumarate reductase, subunit C; KEGG: cvi:CV3367 fumarate reductase, subunit C. | 0.900 |
| Ping_1977 | Ping_3281 | Ping_1977 | Ping_3281 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarate reductase, D subunit; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 0.900 |
| Ping_1977 | sucC | Ping_1977 | Ping_2250 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.633 |
| Ping_1977 | sucD | Ping_1977 | Ping_2249 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.540 |
| Ping_2254 | Ping_1217 | Ping_2254 | Ping_1217 | KEGG: vch:VC2089 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit. | 0.952 |
| Ping_2254 | Ping_1977 | Ping_2254 | Ping_1977 | KEGG: vch:VC2089 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.991 |
| Ping_2254 | Ping_2255 | Ping_2254 | Ping_2255 | KEGG: vch:VC2089 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Succinate dehydrogenase subunit D; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.997 |
| Ping_2254 | Ping_2256 | Ping_2254 | Ping_2256 | KEGG: vch:VC2089 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: vfi:VF0819 succinate dehydrogenase cytochrome b556 subunit. | 0.999 |