| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0113 | Ping_3340 | Ping_0113 | Ping_3340 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | 0.589 |
| Ping_0113 | Ping_3341 | Ping_0113 | Ping_3341 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | 0.595 |
| Ping_0113 | cysG | Ping_0113 | Ping_0298 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.746 |
| Ping_3340 | Ping_0113 | Ping_3340 | Ping_0113 | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.589 |
| Ping_3340 | Ping_3341 | Ping_3340 | Ping_3341 | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | 0.860 |
| Ping_3340 | Ping_3343 | Ping_3340 | Ping_3343 | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | ABC transporter for cobalamin/Fe3+-siderophores ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mbu:Mbur_1545 ABC transporter, ATPase subunit. | 0.830 |
| Ping_3340 | Ping_3344 | Ping_3340 | Ping_3344 | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | Outer membrane transport energization protein ExbB; PFAM: MotA/TolQ/ExbB proton channel; KEGG: ava:Ava_2465 MotA/TolQ/ExbB proton channel; TC 2.C.1.1.1. | 0.693 |
| Ping_3340 | Ping_3345 | Ping_3340 | Ping_3345 | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | PFAM: Biopolymer transport protein ExbD/TolR; KEGG: syf:Synpcc7942_2428 biopolymer transport ExbD like protein; TC 2.C.1.1.1. | 0.624 |
| Ping_3340 | Ping_3346 | Ping_3340 | Ping_3346 | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | Outer membrane transport energization protein TonB; TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: ppr:PBPRA2103 hypothetical TonB protein; TC 2.C.1.1.1. | 0.902 |
| Ping_3340 | fecD | Ping_3340 | Ping_3342 | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | PFAM: transport system permease protein; KEGG: dra:DRB0015 putative hemin transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.875 |
| Ping_3341 | Ping_0113 | Ping_3341 | Ping_0113 | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.595 |
| Ping_3341 | Ping_3340 | Ping_3341 | Ping_3340 | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | 0.860 |
| Ping_3341 | Ping_3343 | Ping_3341 | Ping_3343 | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | ABC transporter for cobalamin/Fe3+-siderophores ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mbu:Mbur_1545 ABC transporter, ATPase subunit. | 0.994 |
| Ping_3341 | Ping_3344 | Ping_3341 | Ping_3344 | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | Outer membrane transport energization protein ExbB; PFAM: MotA/TolQ/ExbB proton channel; KEGG: ava:Ava_2465 MotA/TolQ/ExbB proton channel; TC 2.C.1.1.1. | 0.545 |
| Ping_3341 | Ping_3345 | Ping_3341 | Ping_3345 | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | PFAM: Biopolymer transport protein ExbD/TolR; KEGG: syf:Synpcc7942_2428 biopolymer transport ExbD like protein; TC 2.C.1.1.1. | 0.553 |
| Ping_3341 | Ping_3346 | Ping_3341 | Ping_3346 | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | Outer membrane transport energization protein TonB; TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: ppr:PBPRA2103 hypothetical TonB protein; TC 2.C.1.1.1. | 0.665 |
| Ping_3341 | cysG | Ping_3341 | Ping_0298 | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.445 |
| Ping_3341 | fecD | Ping_3341 | Ping_3342 | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | PFAM: transport system permease protein; KEGG: dra:DRB0015 putative hemin transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.990 |
| Ping_3341 | ribB | Ping_3341 | Ping_1442 | Predicted Fe ABC transporter; PFAM: periplasmic binding protein; KEGG: vfi:VFA0973 ABC transporter, periplasmic component. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.458 |
| Ping_3343 | Ping_3340 | Ping_3343 | Ping_3340 | ABC transporter for cobalamin/Fe3+-siderophores ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mbu:Mbur_1545 ABC transporter, ATPase subunit. | PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pca:Pcar_0454 TonB-dependent receptor, putative. | 0.830 |