| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_0113 | Ping_0757 | Ping_0113 | Ping_0757 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rso:RS02139 hypothetical protein. | 0.471 |
| Ping_0113 | Ping_1289 | Ping_0113 | Ping_1289 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: cps:CPS_0276 hypothetical protein. | 0.951 |
| Ping_0113 | Ping_3536 | Ping_0113 | Ping_3536 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: ppr:PBPRA2942 putative lipoprotein YaeC; Belongs to the nlpA lipoprotein family. | 0.464 |
| Ping_0113 | Ping_3644 | Ping_0113 | Ping_3644 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: cps:CPS_2546 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.944 |
| Ping_0113 | metK | Ping_0113 | Ping_3227 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.947 |
| Ping_0113 | metN | Ping_0113 | Ping_3538 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | D-methionine ABC transporter, ATPase subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.429 |
| Ping_0757 | Ping_0113 | Ping_0757 | Ping_0113 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rso:RS02139 hypothetical protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.471 |
| Ping_0757 | Ping_1008 | Ping_0757 | Ping_1008 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rso:RS02139 hypothetical protein. | TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vch:VC2374 glutamate synthase, small subunit. | 0.583 |
| Ping_0757 | Ping_3536 | Ping_0757 | Ping_3536 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rso:RS02139 hypothetical protein. | TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: ppr:PBPRA2942 putative lipoprotein YaeC; Belongs to the nlpA lipoprotein family. | 0.608 |
| Ping_1008 | Ping_0757 | Ping_1008 | Ping_0757 | TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vch:VC2374 glutamate synthase, small subunit. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rso:RS02139 hypothetical protein. | 0.583 |
| Ping_1008 | Ping_3536 | Ping_1008 | Ping_3536 | TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vch:VC2374 glutamate synthase, small subunit. | TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: ppr:PBPRA2942 putative lipoprotein YaeC; Belongs to the nlpA lipoprotein family. | 0.463 |
| Ping_1008 | Ping_3644 | Ping_1008 | Ping_3644 | TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vch:VC2374 glutamate synthase, small subunit. | KEGG: cps:CPS_2546 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.583 |
| Ping_1289 | Ping_0113 | Ping_1289 | Ping_0113 | KEGG: cps:CPS_0276 hypothetical protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.951 |
| Ping_1289 | Ping_3536 | Ping_1289 | Ping_3536 | KEGG: cps:CPS_0276 hypothetical protein. | TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: ppr:PBPRA2942 putative lipoprotein YaeC; Belongs to the nlpA lipoprotein family. | 0.437 |
| Ping_1289 | Ping_3537 | Ping_1289 | Ping_3537 | KEGG: cps:CPS_0276 hypothetical protein. | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ppr:PBPRA2941 putative ABC-type metal ion transport system,permease component. | 0.520 |
| Ping_1289 | metK | Ping_1289 | Ping_3227 | KEGG: cps:CPS_0276 hypothetical protein. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.770 |
| Ping_1289 | metN | Ping_1289 | Ping_3538 | KEGG: cps:CPS_0276 hypothetical protein. | D-methionine ABC transporter, ATPase subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.660 |
| Ping_3287 | Ping_3536 | Ping_3287 | Ping_3536 | PFAM: protein of unknown function UPF0066; KEGG: ypa:YPA_0546 hypothetical protein. | TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: ppr:PBPRA2942 putative lipoprotein YaeC; Belongs to the nlpA lipoprotein family. | 0.424 |
| Ping_3535 | Ping_3536 | Ping_3535 | Ping_3536 | PFAM: oxidoreductase domain protein; KEGG: vpa:VPA1281 oxidoreductase, Gfo/Idh/MocA family. | TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: ppr:PBPRA2942 putative lipoprotein YaeC; Belongs to the nlpA lipoprotein family. | 0.483 |
| Ping_3535 | metN | Ping_3535 | Ping_3538 | PFAM: oxidoreductase domain protein; KEGG: vpa:VPA1281 oxidoreductase, Gfo/Idh/MocA family. | D-methionine ABC transporter, ATPase subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.505 |