| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ping_1678 | Ping_3682 | Ping_1678 | Ping_3682 | ABC-type uncharacterized transport system auxiliary component-like protein; KEGG: cbu:CBU_0730 hypothetical protein. | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | 0.410 |
| Ping_3359 | Ping_3682 | Ping_3359 | Ping_3682 | Nucleoside diphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: ppr:PBPRA0451 putative MutT/nudix family protein. | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | 0.479 |
| Ping_3359 | birA | Ping_3359 | Ping_0219 | Nucleoside diphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: ppr:PBPRA0451 putative MutT/nudix family protein. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.562 |
| Ping_3359 | nnrE | Ping_3359 | Ping_3243 | Nucleoside diphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: ppr:PBPRA0451 putative MutT/nudix family protein. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.604 |
| Ping_3681 | Ping_3682 | Ping_3681 | Ping_3682 | KEGG: son:SO2875 ISSod10, transposase OrfB. | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | 0.417 |
| Ping_3682 | Ping_1678 | Ping_3682 | Ping_1678 | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | ABC-type uncharacterized transport system auxiliary component-like protein; KEGG: cbu:CBU_0730 hypothetical protein. | 0.410 |
| Ping_3682 | Ping_3359 | Ping_3682 | Ping_3359 | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | Nucleoside diphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: ppr:PBPRA0451 putative MutT/nudix family protein. | 0.479 |
| Ping_3682 | Ping_3681 | Ping_3682 | Ping_3681 | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | KEGG: son:SO2875 ISSod10, transposase OrfB. | 0.417 |
| Ping_3682 | birA | Ping_3682 | Ping_0219 | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.562 |
| Ping_3682 | nnrE | Ping_3682 | Ping_3243 | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.604 |
| birA | Ping_3359 | Ping_0219 | Ping_3359 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Nucleoside diphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: ppr:PBPRA0451 putative MutT/nudix family protein. | 0.562 |
| birA | Ping_3682 | Ping_0219 | Ping_3682 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | 0.562 |
| birA | nnrE | Ping_0219 | Ping_3243 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.557 |
| nnrE | Ping_3359 | Ping_3243 | Ping_3359 | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | Nucleoside diphosphate pyrophosphatase; PFAM: NUDIX hydrolase; KEGG: ppr:PBPRA0451 putative MutT/nudix family protein. | 0.604 |
| nnrE | Ping_3682 | Ping_3243 | Ping_3682 | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | UDP-sugar diphosphatase; PFAM: NUDIX hydrolase; KEGG: wsu:WS0265 hypothetical protein. | 0.604 |
| nnrE | birA | Ping_3243 | Ping_0219 | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.557 |