node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABQ89444.1 | ABQ89564.1 | RoseRS_1035 | RoseRS_1157 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | 0.847 |
ABQ89444.1 | ABQ91273.1 | RoseRS_1035 | RoseRS_2905 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; XYPPX repeat-containing protein; phosphopantetheine-binding; KR. | 0.837 |
ABQ89444.1 | mnmE | RoseRS_1035 | RoseRS_3161 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.857 |
ABQ89444.1 | rplC | RoseRS_1035 | RoseRS_1185 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.859 |
ABQ89444.1 | rplK | RoseRS_1035 | RoseRS_3326 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.838 |
ABQ89444.1 | rplM | RoseRS_1035 | RoseRS_1155 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.863 |
ABQ89444.1 | rplO | RoseRS_1035 | RoseRS_1166 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.841 |
ABQ89444.1 | rplT | RoseRS_1035 | RoseRS_1034 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.913 |
ABQ89444.1 | rplU | RoseRS_1035 | RoseRS_2695 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.845 |
ABQ89444.1 | rsfS | RoseRS_1035 | RoseRS_3248 | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.852 |
ABQ89564.1 | ABQ89444.1 | RoseRS_1157 | RoseRS_1035 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.847 |
ABQ89564.1 | ABQ91273.1 | RoseRS_1157 | RoseRS_2905 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; XYPPX repeat-containing protein; phosphopantetheine-binding; KR. | 0.968 |
ABQ89564.1 | mnmE | RoseRS_1157 | RoseRS_3161 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.890 |
ABQ89564.1 | rplC | RoseRS_1157 | RoseRS_1185 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.996 |
ABQ89564.1 | rplK | RoseRS_1157 | RoseRS_3326 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.992 |
ABQ89564.1 | rplM | RoseRS_1157 | RoseRS_1155 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.998 |
ABQ89564.1 | rplO | RoseRS_1157 | RoseRS_1166 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.997 |
ABQ89564.1 | rplT | RoseRS_1157 | RoseRS_1034 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.991 |
ABQ89564.1 | rplU | RoseRS_1157 | RoseRS_2695 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.991 |
ABQ89564.1 | rsfS | RoseRS_1157 | RoseRS_3248 | PFAM: ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.925 |