| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABQ88507.1 | ABQ90281.1 | RoseRS_0064 | RoseRS_1892 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine kinase; PFAM: aminoglycoside phosphotransferase. | 0.816 |
| ABQ88507.1 | ABQ90358.1 | RoseRS_0064 | RoseRS_1971 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | 0.934 |
| ABQ88507.1 | ABQ90416.1 | RoseRS_0064 | RoseRS_2031 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.583 |
| ABQ88507.1 | ABQ91351.1 | RoseRS_0064 | RoseRS_2987 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | 0.934 |
| ABQ88507.1 | ABQ91441.1 | RoseRS_0064 | RoseRS_3078 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.553 |
| ABQ88507.1 | ABQ91442.1 | RoseRS_0064 | RoseRS_3079 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.913 |
| ABQ88507.1 | ABQ91443.1 | RoseRS_0064 | RoseRS_3080 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.543 |
| ABQ88507.1 | ABQ92255.1 | RoseRS_0064 | RoseRS_3902 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.877 |
| ABQ88507.1 | metXA | RoseRS_0064 | RoseRS_1759 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.755 |
| ABQ90281.1 | ABQ88507.1 | RoseRS_1892 | RoseRS_0064 | Homoserine kinase; PFAM: aminoglycoside phosphotransferase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.816 |
| ABQ90281.1 | ABQ90358.1 | RoseRS_1892 | RoseRS_1971 | Homoserine kinase; PFAM: aminoglycoside phosphotransferase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | 0.913 |
| ABQ90281.1 | ABQ91351.1 | RoseRS_1892 | RoseRS_2987 | Homoserine kinase; PFAM: aminoglycoside phosphotransferase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | 0.913 |
| ABQ90281.1 | ABQ91442.1 | RoseRS_1892 | RoseRS_3079 | Homoserine kinase; PFAM: aminoglycoside phosphotransferase. | TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.908 |
| ABQ90281.1 | ABQ91443.1 | RoseRS_1892 | RoseRS_3080 | Homoserine kinase; PFAM: aminoglycoside phosphotransferase. | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.921 |
| ABQ90281.1 | ABQ92255.1 | RoseRS_1892 | RoseRS_3902 | Homoserine kinase; PFAM: aminoglycoside phosphotransferase. | TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.902 |
| ABQ90358.1 | ABQ88507.1 | RoseRS_1971 | RoseRS_0064 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.934 |
| ABQ90358.1 | ABQ90281.1 | RoseRS_1971 | RoseRS_1892 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | Homoserine kinase; PFAM: aminoglycoside phosphotransferase. | 0.913 |
| ABQ90358.1 | ABQ90416.1 | RoseRS_1971 | RoseRS_2031 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.620 |
| ABQ90358.1 | ABQ91351.1 | RoseRS_1971 | RoseRS_2987 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | 0.915 |
| ABQ90358.1 | ABQ91441.1 | RoseRS_1971 | RoseRS_3078 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding. | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.955 |