| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_0068 | Cphy_0069 | Cphy_0068 | Cphy_0069 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | KEGG: cth:Cthe_0079 hypothetical protein. | 0.528 |
| Cphy_0068 | Cphy_0268 | Cphy_0068 | Cphy_0268 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | 0.620 |
| Cphy_0068 | Cphy_1337 | Cphy_0068 | Cphy_1337 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | PFAM: cell cycle protein; penicillin-binding protein transpeptidase; KEGG: ckl:CKL_3568 predicted peptidoglycan synthetase. | 0.718 |
| Cphy_0068 | Cphy_1886 | Cphy_0068 | Cphy_1886 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | PFAM: NLP/P60 protein; Peptidoglycan-binding domain 1 protein; KEGG: gtn:GTNG_3106 cell wall lytic activity. | 0.623 |
| Cphy_0068 | Cphy_2257 | Cphy_0068 | Cphy_2257 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | PFAM: protein of unknown function DUF187; KEGG: btk:BT9727_0818 conserved hypothetical protein and possible S-layer protein fusion. | 0.664 |
| Cphy_0068 | Cphy_2818 | Cphy_0068 | Cphy_2818 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | PFAM: cell wall hydrolase/autolysin; KEGG: tte:TTE2424 N-acetylmuramoyl-L-alanine amidase. | 0.574 |
| Cphy_0068 | Cphy_3607 | Cphy_0068 | Cphy_3607 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | PFAM: peptidase M23B; KEGG: tte:TTE1975 membrane proteins related to metalloendopeptidase. | 0.610 |
| Cphy_0068 | guaA | Cphy_0068 | Cphy_0264 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.659 |
| Cphy_0068 | nnrD | Cphy_0068 | Cphy_0904 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.680 |
| Cphy_0068 | secF | Cphy_0068 | Cphy_0716 | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.527 |
| Cphy_0069 | Cphy_0068 | Cphy_0069 | Cphy_0068 | KEGG: cth:Cthe_0079 hypothetical protein. | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | 0.528 |
| Cphy_0268 | Cphy_0068 | Cphy_0268 | Cphy_0068 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | 0.620 |
| Cphy_0268 | Cphy_1337 | Cphy_0268 | Cphy_1337 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | PFAM: cell cycle protein; penicillin-binding protein transpeptidase; KEGG: ckl:CKL_3568 predicted peptidoglycan synthetase. | 0.487 |
| Cphy_0268 | guaA | Cphy_0268 | Cphy_0264 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.552 |
| Cphy_0268 | nnrD | Cphy_0268 | Cphy_0904 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.638 |
| Cphy_0268 | secF | Cphy_0268 | Cphy_0716 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.676 |
| Cphy_1337 | Cphy_0068 | Cphy_1337 | Cphy_0068 | PFAM: cell cycle protein; penicillin-binding protein transpeptidase; KEGG: ckl:CKL_3568 predicted peptidoglycan synthetase. | PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: syn:slr0891 N-acetylmuramoyl-L-alanine amidase. | 0.718 |
| Cphy_1337 | Cphy_0268 | Cphy_1337 | Cphy_0268 | PFAM: cell cycle protein; penicillin-binding protein transpeptidase; KEGG: ckl:CKL_3568 predicted peptidoglycan synthetase. | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | 0.487 |
| Cphy_1337 | Cphy_1886 | Cphy_1337 | Cphy_1886 | PFAM: cell cycle protein; penicillin-binding protein transpeptidase; KEGG: ckl:CKL_3568 predicted peptidoglycan synthetase. | PFAM: NLP/P60 protein; Peptidoglycan-binding domain 1 protein; KEGG: gtn:GTNG_3106 cell wall lytic activity. | 0.471 |
| Cphy_1337 | Cphy_3607 | Cphy_1337 | Cphy_3607 | PFAM: cell cycle protein; penicillin-binding protein transpeptidase; KEGG: ckl:CKL_3568 predicted peptidoglycan synthetase. | PFAM: peptidase M23B; KEGG: tte:TTE1975 membrane proteins related to metalloendopeptidase. | 0.693 |