STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Cphy_0091Protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; KEGG: cth:Cthe_0427 serine phosphatase. (390 aa)    
Predicted Functional Partners:
Cphy_2838
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: pth:PTH_0142 hypothetical protein.
  
  
 0.971
Cphy_0092
Putative PAS/PAC sensor protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; hydrogenase large subunit domain protein; Fe-S cluster domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: tte:TTE0697 ferredoxin 2.
 
     0.945
Cphy_0093
KEGG: cth:Cthe_0425 hypothetical protein.
 
    0.937
Cphy_3799
KEGG: cth:Cthe_0334 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.918
Cphy_0245
KEGG: cth:Cthe_2622 hypothetical protein.
   
    0.904
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.863
Cphy_0090
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; hydrogenase large subunit domain protein; KEGG: cbe:Cbei_0327 ferredoxin hydrogenase.
 
     0.845
Cphy_2703
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: cth:Cthe_0477 flagellar motor switch protein FliM.
  
    0.818
Cphy_2082
PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cbe:Cbei_4439 biotin and thiamin synthesis associated.
   
    0.815
Cphy_1136
KEGG: nmu:Nmul_A0328 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
  
 0.762
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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