| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_0002 | Cphy_0105 | Cphy_0002 | Cphy_0105 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | 0.488 |
| Cphy_0002 | Cphy_0106 | Cphy_0002 | Cphy_0106 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: tte:TTE2692 hypothetical protein. | 0.530 |
| Cphy_0002 | Cphy_2365 | Cphy_0002 | Cphy_2365 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: amt:Amet_3681 hypothetical protein. | 0.923 |
| Cphy_0002 | Cphy_3756 | Cphy_0002 | Cphy_3756 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.657 |
| Cphy_0002 | polA | Cphy_0002 | Cphy_2803 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.993 |
| Cphy_0104 | Cphy_0105 | Cphy_0104 | Cphy_0105 | KEGG: cpr:CPR_1519 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | 0.494 |
| Cphy_0104 | Cphy_0106 | Cphy_0104 | Cphy_0106 | KEGG: cpr:CPR_1519 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: tte:TTE2692 hypothetical protein. | 0.505 |
| Cphy_0104 | Cphy_3483 | Cphy_0104 | Cphy_3483 | KEGG: cpr:CPR_1519 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cth:Cthe_0559 single-strand binding protein/primosomal replication protein N. | 0.403 |
| Cphy_0104 | polA | Cphy_0104 | Cphy_2803 | KEGG: cpr:CPR_1519 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.517 |
| Cphy_0105 | Cphy_0002 | Cphy_0105 | Cphy_0002 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.488 |
| Cphy_0105 | Cphy_0104 | Cphy_0105 | Cphy_0104 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | KEGG: cpr:CPR_1519 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. | 0.494 |
| Cphy_0105 | Cphy_0106 | Cphy_0105 | Cphy_0106 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: tte:TTE2692 hypothetical protein. | 0.944 |
| Cphy_0105 | Cphy_0407 | Cphy_0105 | Cphy_0407 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | KEGG: cdf:CD3250 hypothetical protein. | 0.715 |
| Cphy_0105 | Cphy_2365 | Cphy_0105 | Cphy_2365 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | KEGG: amt:Amet_3681 hypothetical protein. | 0.709 |
| Cphy_0105 | Cphy_3483 | Cphy_0105 | Cphy_3483 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cth:Cthe_0559 single-strand binding protein/primosomal replication protein N. | 0.583 |
| Cphy_0105 | Cphy_3550 | Cphy_0105 | Cphy_3550 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | KEGG: tte:TTE2207 hypothetical protein. | 0.493 |
| Cphy_0105 | Cphy_3756 | Cphy_0105 | Cphy_3756 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.858 |
| Cphy_0105 | murC | Cphy_0105 | Cphy_0107 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.648 |
| Cphy_0105 | polA | Cphy_0105 | Cphy_2803 | SMART: AAA ATPase; KEGG: cno:NT01CX_0917 DNA replication protein DnaC, putative; Belongs to the DnaA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.664 |
| Cphy_0106 | Cphy_0002 | Cphy_0106 | Cphy_0002 | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: tte:TTE2692 hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.530 |