| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_0002 | Cphy_0268 | Cphy_0002 | Cphy_0268 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | 0.956 |
| Cphy_0002 | Cphy_0622 | Cphy_0002 | Cphy_0622 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | SMART: DNA mismatch repair protein MutS domain protein; KEGG: cdf:CD3408 putative DNA mismatch repair protein. | 0.757 |
| Cphy_0002 | Cphy_1154 | Cphy_0002 | Cphy_1154 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: cac:CAC2687 RecQ protein, superfamily II DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | 0.889 |
| Cphy_0002 | Cphy_1160 | Cphy_0002 | Cphy_1160 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: DNA mismatch repair protein MutS domain protein; KEGG: cpr:CPR_0886 MutS domain V protein. | 0.757 |
| Cphy_0002 | Cphy_2064 | Cphy_0002 | Cphy_2064 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Mismatch repair ATPase (MutS family)-like protein; KEGG: cpr:CPR_0886 MutS domain V protein. | 0.757 |
| Cphy_0002 | Cphy_2383 | Cphy_0002 | Cphy_2383 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: DNA mismatch repair protein MutS domain protein; KEGG: cpr:CPR_0886 MutS domain V protein. | 0.757 |
| Cphy_0002 | Cphy_2838 | Cphy_0002 | Cphy_2838 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: pth:PTH_0142 hypothetical protein. | 0.494 |
| Cphy_0002 | mutS | Cphy_0002 | Cphy_2381 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.800 |
| Cphy_0002 | polA | Cphy_0002 | Cphy_2803 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.993 |
| Cphy_0002 | recA | Cphy_0002 | Cphy_2439 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.945 |
| Cphy_0268 | Cphy_0002 | Cphy_0268 | Cphy_0002 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.956 |
| Cphy_0268 | Cphy_0622 | Cphy_0268 | Cphy_0622 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | SMART: DNA mismatch repair protein MutS domain protein; KEGG: cdf:CD3408 putative DNA mismatch repair protein. | 0.840 |
| Cphy_0268 | Cphy_1154 | Cphy_0268 | Cphy_1154 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | KEGG: cac:CAC2687 RecQ protein, superfamily II DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | 0.838 |
| Cphy_0268 | Cphy_1160 | Cphy_0268 | Cphy_1160 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | PFAM: DNA mismatch repair protein MutS domain protein; KEGG: cpr:CPR_0886 MutS domain V protein. | 0.845 |
| Cphy_0268 | Cphy_2064 | Cphy_0268 | Cphy_2064 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | Mismatch repair ATPase (MutS family)-like protein; KEGG: cpr:CPR_0886 MutS domain V protein. | 0.815 |
| Cphy_0268 | Cphy_2383 | Cphy_0268 | Cphy_2383 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | PFAM: DNA mismatch repair protein MutS domain protein; KEGG: cpr:CPR_0886 MutS domain V protein. | 0.837 |
| Cphy_0268 | Cphy_2838 | Cphy_0268 | Cphy_2838 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: pth:PTH_0142 hypothetical protein. | 0.940 |
| Cphy_0268 | mutS | Cphy_0268 | Cphy_2381 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.836 |
| Cphy_0268 | polA | Cphy_0268 | Cphy_2803 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.956 |
| Cphy_0268 | recA | Cphy_0268 | Cphy_2439 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: pfo:Pfl_4625 histidine kinase. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.860 |
