Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cphy_0390TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: cno:NT01CX_1200 putative amidohydrolase; Belongs to the peptidase M20A family. (439 aa)    
Predicted Functional Partners:
Cphy_0389
PFAM: protein of unknown function DUF6 transmembrane; KEGG: fjo:Fjoh_4335 protein of unknown function DUF6, transmembrane.
       0.551
Cphy_0391
KEGG: rba:RB7999 hypothetical protein; Belongs to the DapA family.
     
 0.523
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.499
Cphy_2724
Mg chelatase, subunit ChlI; KEGG: tte:TTE1455 predicted ATPase with chaperone activity; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase.
  
   0.486
Cphy_0392
PFAM: NAD-dependent epimerase/dehydratase; KEGG: rba:RB7998 hypothetical protein.
       0.470
Cphy_1481
TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; KEGG: cpr:CPR_2055 molybdenum cofactor synthesis protein.
 
     0.456
Cphy_1501
N-acyl-D-glutamate deacylase; PFAM: D-aminoacylase domain protein; Amidohydrolase 3; KEGG: drm:Dred_0263 N-acyl-D-amino-acid deacylase.
 
     0.446
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.443
Cphy_2753
PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: oih:OB2060 hypothetical protein.
 
    0.414
Cphy_2754
TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: oih:OB2059 hypothetical conserved protein; Belongs to the RimK family.
 
    0.407
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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