STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Cphy_0455PFAM: aminotransferase class I and II; KEGG: cbf:CLI_1497 aminotransferase, classes I and II. (397 aa)    
Predicted Functional Partners:
Cphy_1227
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: cbh:CLC_0782 cystathionine beta-lyase.
 
 
 0.972
Cphy_3258
PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: cth:Cthe_0645 homocysteine S-methyltransferase.
     
 0.941
Cphy_0010
KEGG: cbe:Cbei_0766 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase.
   
 0.923
Cphy_0011
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cbe:Cbei_4356 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.922
Cphy_1228
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cth:Cthe_1560 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
    
 0.922
Cphy_2760
O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: bfs:BF3351 putative cysteine biosynthesis related protein; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
   
 0.920
Cphy_3530
PFAM: aminotransferase class I and II; KEGG: dsy:DSY1222 hypothetical protein.
    
 0.909
luxS
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.907
Cphy_2184
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. Belongs to the peptidase M17 family.
  
 
  0.811
Cphy_2441
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: cbe:Cbei_1562 threonine dehydratase.
    
  0.810
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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