STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_0480TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: amt:Amet_2220 stage V sporulation AD family protein. (355 aa)    
Predicted Functional Partners:
Cphy_0479
TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: drm:Dred_1106 SpoVA protein.
 
  
 0.986
Cphy_0481
TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; KEGG: tte:TTE1321 sporulation protein.
 
  
 0.983
gpr
GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.929
Cphy_0751
PFAM: GerA spore germination protein; KEGG: cpe:CPE0984 stage V sporulation protein AF.
 
  
 0.867
Cphy_2497
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.858
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.842
Cphy_0476
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist.
 
   
 0.835
Cphy_0478
RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.817
Cphy_0127
TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T.
  
   
 0.811
Cphy_0829
PFAM: GerA spore germination protein; KEGG: ctc:CTC01776 spore germination protein KA.
  
  
 0.809
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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