| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cphy_0127 | Cphy_0476 | Cphy_0127 | Cphy_0476 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | 0.782 |
| Cphy_0127 | Cphy_0478 | Cphy_0127 | Cphy_0478 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.750 |
| Cphy_0127 | Cphy_0479 | Cphy_0127 | Cphy_0479 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: drm:Dred_1106 SpoVA protein. | 0.774 |
| Cphy_0127 | Cphy_0480 | Cphy_0127 | Cphy_0480 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: amt:Amet_2220 stage V sporulation AD family protein. | 0.811 |
| Cphy_0127 | Cphy_0481 | Cphy_0127 | Cphy_0481 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; KEGG: tte:TTE1321 sporulation protein. | 0.781 |
| Cphy_0127 | Cphy_0751 | Cphy_0127 | Cphy_0751 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | PFAM: GerA spore germination protein; KEGG: cpe:CPE0984 stage V sporulation protein AF. | 0.733 |
| Cphy_0127 | Cphy_0829 | Cphy_0127 | Cphy_0829 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | PFAM: GerA spore germination protein; KEGG: ctc:CTC01776 spore germination protein KA. | 0.770 |
| Cphy_0127 | Cphy_2524 | Cphy_0127 | Cphy_2524 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: pth:PTH_1166 hypothetical protein. | 0.840 |
| Cphy_0127 | gpr | Cphy_0127 | Cphy_2317 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.800 |
| Cphy_0127 | spoIIAB | Cphy_0127 | Cphy_0477 | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.865 |
| Cphy_0476 | Cphy_0127 | Cphy_0476 | Cphy_0127 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: cpe:CPE2482 stage V sprulation protein T. | 0.782 |
| Cphy_0476 | Cphy_0478 | Cphy_0476 | Cphy_0478 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.964 |
| Cphy_0476 | Cphy_0479 | Cphy_0476 | Cphy_0479 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: drm:Dred_1106 SpoVA protein. | 0.844 |
| Cphy_0476 | Cphy_0480 | Cphy_0476 | Cphy_0480 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: amt:Amet_2220 stage V sporulation AD family protein. | 0.835 |
| Cphy_0476 | Cphy_0481 | Cphy_0476 | Cphy_0481 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; KEGG: tte:TTE1321 sporulation protein. | 0.823 |
| Cphy_0476 | Cphy_0751 | Cphy_0476 | Cphy_0751 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | PFAM: GerA spore germination protein; KEGG: cpe:CPE0984 stage V sporulation protein AF. | 0.810 |
| Cphy_0476 | Cphy_0829 | Cphy_0476 | Cphy_0829 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | PFAM: GerA spore germination protein; KEGG: ctc:CTC01776 spore germination protein KA. | 0.708 |
| Cphy_0476 | Cphy_2524 | Cphy_0476 | Cphy_2524 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: pth:PTH_1166 hypothetical protein. | 0.823 |
| Cphy_0476 | gpr | Cphy_0476 | Cphy_2317 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.757 |
| Cphy_0476 | spoIIAB | Cphy_0476 | Cphy_0477 | Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_2212 anti-sigma-factor antagonist. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.997 |