STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_0675KEGG: dsy:DSY2128 hypothetical protein. (264 aa)    
Predicted Functional Partners:
Cphy_3607
PFAM: peptidase M23B; KEGG: tte:TTE1975 membrane proteins related to metalloendopeptidase.
  
  
 0.672
Cphy_1594
KEGG: pth:PTH_0265 hypothetical membrane protein.
  
 
 0.614
Cphy_1726
Hypothetical protein.
  
 
 0.614
Cphy_1798
KEGG: cha:CHAB381_0329 mercuric transport protein periplasmic component.
  
  
 0.582
Cphy_2948
KEGG: ckl:CKL_3246 hypothetical protein.
  
 
 0.514
Cphy_0676
Hypothetical protein; KEGG: bcz:BCZK1145 acetyltransferase, GNAT family.
 
     0.465
Cphy_2563
TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: drm:Dred_2536 ribonuclease, Rne/Rng family.
  
  
 0.443
Cphy_2202
PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein.
     
 0.440
Cphy_2589
PFAM: protein of unknown function DUF214; KEGG: efa:EF1321 permease domain protein.
  
  
 0.425
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.422
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.